Role of exosomes in the pathogenesis, diagnosis, and treatment of central nervous system diseases
Y Fan, Z Chen, M Zhang - Journal of Translational Medicine, 2022 - Springer
Central nervous system (CNS) diseases, such as multiple sclerosis, Alzheimer's disease
(AD), and Parkinson's disease (PD), affect millions of people around the world. Great efforts …
(AD), and Parkinson's disease (PD), affect millions of people around the world. Great efforts …
[HTML][HTML] New strategies of neurodegenerative disease treatment with extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs)
CP Palanisamy, JJ Pei, P Alugoju, NVA Anthikapalli… - Theranostics, 2023 - ncbi.nlm.nih.gov
Neurodegenerative diseases are characterized by the progressive loss of neurons and
intricate interactions between different cell types within the affected regions. Reliable …
intricate interactions between different cell types within the affected regions. Reliable …
Exosomes derived from bone marrow mesenchymal stromal cells promote remyelination and reduce neuroinflammation in the demyelinating central nervous system
J Zhang, BA Buller, ZG Zhang, Y Zhang, M Lu… - Experimental …, 2022 - Elsevier
Injury of oligodendrocytes (OLs) induces demyelination, and patients with
neurodegenerative diseases exhibit demyelination concomitantly with neurological deficit …
neurodegenerative diseases exhibit demyelination concomitantly with neurological deficit …
Mesenchymal stem/stromal cell-derived exosomes in regenerative medicine and cancer; overview of development, challenges, and opportunities
A Hassanzadeh, HS Rahman, A Markov… - Stem cell research & …, 2021 - Springer
Recently, mesenchymal stem/stromal cells (MSCs) and their widespread biomedical
applications have attracted great consideration from the scientific community around the …
applications have attracted great consideration from the scientific community around the …
Mesenchymal stem cell-derived exosome: a promising alternative in the therapy of Alzheimer's disease
M Guo, Z Yin, F Chen, P Lei - Alzheimer's Research & Therapy, 2020 - Springer
Alzheimer's disease (AD) has been a devastating public health with the development of
global aging. Approaches for reducing the current AD epidemic are becoming a primary …
global aging. Approaches for reducing the current AD epidemic are becoming a primary …
[HTML][HTML] MSC-derived exosomes promote recovery from traumatic brain injury via microglia/macrophages in rat
Y Chen, J Li, B Ma, N Li, S Wang, Z Sun, C Xue… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Traumatic brain injury (TBI) is a leading cause of morbidity and mortality in young individuals
worldwide. There is currently no effective clinical treatment for TBI, but mesenchymal stem …
worldwide. There is currently no effective clinical treatment for TBI, but mesenchymal stem …
Mesenchymal stem cell-derived exosomes as a new therapeutic strategy in the brain tumors
E Ghasempour, S Hesami, E Movahed… - Stem Cell Research & …, 2022 - Springer
Brain tumors are one of the most mortal cancers, leading to many deaths among kids and
adults. Surgery, chemotherapy, and radiotherapy are available options for brain tumor …
adults. Surgery, chemotherapy, and radiotherapy are available options for brain tumor …
Intranasal delivery of mesenchymal stem cells-derived extracellular vesicles for the treatment of neurological diseases
Neurological disorders are diseases of the central nervous system (CNS), characterized by
a progressive degeneration of cells and deficiencies in neural functions. Mesenchymal stem …
a progressive degeneration of cells and deficiencies in neural functions. Mesenchymal stem …
Mesenchymal stromal/stem cells and their exosomes application in the treatment of intervertebral disc disease: A promising frontier
G Widjaja, AT Jalil, HS Budi, WK Abdelbasset… - International …, 2022 - Elsevier
Today, the application of mesenchymal stromal/stem cells (MSCs) and their exosomes to
treat degenerative diseases has received attention. Due to the characteristics of these cells …
treat degenerative diseases has received attention. Due to the characteristics of these cells …
Advances in exosomes‐based drug delivery systems
C Gutierrez‐Millan, C Calvo Díaz… - Macromolecular …, 2021 - Wiley Online Library
Exosomes, a subgroup of extracellular vesicles, are important mediators of long‐distance
intercellular communication and are involved in a diverse range of biological processes …
intercellular communication and are involved in a diverse range of biological processes …