Chlamydia cell biology and pathogenesis

C Elwell, K Mirrashidi, J Engel - Nature Reviews Microbiology, 2016 - nature.com
Chlamydia spp. are important causes of human disease for which no effective vaccine
exists. These obligate intracellular pathogens replicate in a specialized membrane …

Peptidoglycan in obligate intracellular bacteria

C Otten, M Brilli, W Vollmer, PH Viollier… - Molecular …, 2018 - Wiley Online Library
Peptidoglycan is the predominant stress‐bearing structure in the cell envelope of most
bacteria, and also a potent stimulator of the eukaryotic immune system. Obligate intracellular …

Regulated proteolysis of a cross-link–specific peptidoglycan hydrolase contributes to bacterial morphogenesis

SK Singh, S Parveen, L SaiSree… - Proceedings of the …, 2015 - National Acad Sciences
Bacterial growth and morphogenesis are intimately coupled to expansion of peptidoglycan
(PG), an extensively cross-linked macromolecule that forms a protective mesh-like sacculus …

Redefining the roles of the FtsZ-ring in bacterial cytokinesis

J Xiao, ED Goley - Current opinion in microbiology, 2016 - Elsevier
Highlights•Bacterial cell division requires generation of constrictive force.•Membrane-
associated FtsZ can generate force in vitro.•FtsZ-generated force is limited and does not set …

Molecular mechanisms for the evolution of bacterial morphologies and growth modes

AM Randich, YV Brun - Frontiers in microbiology, 2015 - frontiersin.org
Bacteria exhibit a rich diversity of morphologies. Within this diversity, there is a uniformity of
shape for each species that is replicated faithfully each generation, suggesting that bacterial …

Evolutionary Cell Biology of Division Mode in the Bacterial Planctomycetes-Verrucomicrobia- Chlamydiae Superphylum

E Rivas-Marín, I Canosa, DP Devos - Frontiers in microbiology, 2016 - frontiersin.org
Bacteria from the Planctomycetes, Verrucomicrobia, and Chlamydiae (PVC) superphylum
are exceptions to the otherwise dominant mode of division by binary fission, which is based …

[HTML][HTML] Insight in the biology of Chlamydia-related bacteria

F Bayramova, N Jacquier, G Greub - Microbes and infection, 2018 - Elsevier
The Chlamydiales order is composed of obligate intracellular bacteria and includes the
Chlamydiaceae family and several family-level lineages called Chlamydia-related bacteria …

Bacterial actin and tubulin homologs in cell growth and division

KK Busiek, W Margolin - Current Biology, 2015 - cell.com
In contrast to the elaborate cytoskeletal machines harbored by eukaryotic cells, such as
mitotic spindles, cytoskeletal structures detectable by typical negative stain electron …

The role of peptidoglycan in chlamydial cell division: towards resolving the chlamydial anomaly

N Jacquier, PH Viollier, G Greub - FEMS microbiology reviews, 2015 - academic.oup.com
Chlamydiales are obligate intracellular bacteria including some important pathogens
causing trachoma, genital tract infections and pneumonia, among others. They share an …

An NlpC/P60 protein catalyzes a key step in peptidoglycan recycling at the intersection of energy recovery, cell division and immune evasion in the intracellular …

J Reuter, C Otten, N Jacquier, J Lee… - PLoS …, 2023 - journals.plos.org
The obligate intracellular Chlamydiaceae do not need to resist osmotic challenges and thus
lost their cell wall in the course of evolution. Nevertheless, these pathogens maintain a …