Tissue-type plasminogen activator-primed human iPSC-derived neural progenitor cells promote...

SARS-CoV-2 infects human brain organoids causing cell death and loss of synapses that can be rescued by treatment with Sofosbuvir

P Mesci, JS de Souza, L Martin-Sancho, A Macia… - PLoS …, 2022 - journals.plos.org

The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the causative
agent of coronavirus disease 2019 (COVID-19), which was rapidly declared a pandemic by …

被引用次数：47 相关文章所有 11 个版本

[PDF] mdpi.com

Pluripotent stem cells for spinal cord injury repair

M Martin-Lopez, B Fernandez-Muñoz, S Canovas - Cells, 2021 - mdpi.com

Spinal cord injury (SCI) is a devastating condition of the central nervous system that strongly
reduces the patient's quality of life and has large financial costs for the healthcare system …

被引用次数：16 相关文章所有 9 个版本

[PDF] physiology.org Full View

Plasminogen activator receptor assemblies in cell signaling, innate immunity, and inflammation

SL Gonias - American Journal of Physiology-Cell …, 2021 - journals.physiology.org

Tissue-type plasminogen activator (tPA) and urokinase-type plasminogen activator (uPA)
are serine proteases and major activators of fibrinolysis in mammalian systems. Because …

被引用次数：27 相关文章所有 6 个版本

[PDF] springer.com

Apelin alleviated neuroinflammation and promoted endogenous neural stem cell proliferation and differentiation after spinal cord injury in rats

Q Liu, S Zhou, X Wang, C Gu, Q Guo, X Li… - Journal of …, 2022 - Springer

Background Spinal cord injury (SCI) causes devastating neurological damage, including
secondary injuries dominated by neuroinflammation. The role of Apelin, an endogenous …

被引用次数：30 相关文章所有 12 个版本

[HTML] nih.gov

[HTML][HTML] Serine proteases and chemokines in neurotrauma: new targets for immune modulating therapeutics in spinal cord injury

RN Beladi, KS Varkoly, L Schutz, L Zhang… - Current …, 2021 - ncbi.nlm.nih.gov

Progressive neurological damage after brain or spinal cord trauma causes loss of motor
function and treatment is very limited. Clotting and hemorrhage occur early after spinal cord …

被引用次数：13 相关文章所有 10 个版本

[HTML] sciencedirect.com

[HTML][HTML] Enzymatically inactive tissue-type plasminogen activator reverses disease progression in the dextran sulfate sodium mouse model of inflammatory bowel …

L Das, MA Banki, P Azmoon, D Pizzo… - The American Journal of …, 2021 - Elsevier

Enzymatically inactive tissue-type plasminogen activator (EI-tPA) does not activate
fibrinolysis, but interacts with the N-methyl-d-aspartate receptor (NMDA-R) and low-density …

被引用次数：10 相关文章所有 7 个版本

[PDF] frontiersin.org

Building on a Solid Foundation: Adding Relevance and Reproducibility to Neurological Modeling Using Human Pluripotent Stem Cells

E Knock, LM Julian - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org

The brain is our most complex and least understood organ. Animal models have long been
the most versatile tools available to dissect brain form and function; however, the human …

被引用次数：1 相关文章所有 6 个版本