Recent trends in praziquantel nanoformulations for helminthiasis treatment
AC Mengarda, B Iles, JP F. Longo… - Expert Opinion on Drug …, 2022 - Taylor & Francis
Introduction Infections caused by parasitic flatworms impose a considerable worldwide
health burden. Recently, World Health Organization launched its roadmap for neglected …
health burden. Recently, World Health Organization launched its roadmap for neglected …
Nanoparticles for antiparasitic drug delivery
Y Sun, D Chen, Y Pan, W Qu, H Hao, X Wang, Z Liu… - Drug Delivery, 2019 - Taylor & Francis
As an emerging novel drug carrier, nanoparticles provide a promising way for effective
treatment of parasitic diseases by overcoming the shortcomings of low bioavailability, poor …
treatment of parasitic diseases by overcoming the shortcomings of low bioavailability, poor …
Drug discovery technologies: Caenorhabditis elegans as a model for anthelmintic therapeutics
D Sepúlveda‐Crespo, RM Reguera… - Medicinal research …, 2020 - Wiley Online Library
Helminthiasis is one of the gravest problems worldwide. There is a growing concern on less
available anthelmintics and the emergence of resistance creating a major threat to human …
available anthelmintics and the emergence of resistance creating a major threat to human …
[HTML][HTML] Potential application of nanotechnology in the treatment, diagnosis, and prevention of schistosomiasis
Schistosomiasis is one of the neglected tropical diseases that affect millions of people
worldwide. Globally, it affects the economically poor countries, usually with the scarcity of …
worldwide. Globally, it affects the economically poor countries, usually with the scarcity of …
[HTML][HTML] A review of nanotechnology for targeted anti-schistosomal therapy
Schistosomiasis is one of the major parasitic diseases and second most prevalent among
the group of neglected diseases. The prevalence of schistosomiasis may be due to …
the group of neglected diseases. The prevalence of schistosomiasis may be due to …
The idiosyncratic efficacy of spironolactone-loaded PLGA nanoparticles against murine intestinal schistosomiasis
Background Schistosomiasis is a chronic debilitating parasitic disease accompanied with
severe mortality rates. Although praziquantel (PZQ) acts as the sole drug for the …
severe mortality rates. Although praziquantel (PZQ) acts as the sole drug for the …
Loading praziquantel within solid lipid nanoparticles improved its schistosomicidal efficacy against the juvenile stage
NMFH Mogahed, MM El-Temsahy… - Experimental …, 2023 - Elsevier
Schistosomiasis is a devastating endemic water born tropical disease caused by a parasitic
flat worm of the genus Schistosoma. It is usually associated with poverty, causing significant …
flat worm of the genus Schistosoma. It is usually associated with poverty, causing significant …
Brain-targeted delivery of Valsartan using solid lipid nanoparticles labeled with Rhodamine B; a promising technique for mitigating the negative effects of stroke
The brain is a vital organ that is protected from the general circulation and is distinguished
by the presence of a relatively impermeable blood brain barrier (BBB). Blood brain barrier …
by the presence of a relatively impermeable blood brain barrier (BBB). Blood brain barrier …
A single oral dose of celecoxib-loaded solid lipid nanoparticles for treatment of different developmental stages of experimental schistosomiasis mansoni
EI Ibrahim, IF Abou-El-Naga, MM El-Temsahy… - Acta Tropica, 2022 - Elsevier
Schistosomiasis, a neglected tropical parasitic disease, is associated with severe pathology,
mortality and economic loss. The treatment and control of schistosomiasis depends mainly …
mortality and economic loss. The treatment and control of schistosomiasis depends mainly …
[HTML][HTML] Single oral fixed-dose praziquantel-miltefosine nanocombination for effective control of experimental schistosomiasis mansoni
MM Eissa, MZ El-Azzouni, LK El-Khordagui… - Parasites & vectors, 2020 - Springer
Background The control of schistosomiasis has been centered to date on a single drug,
praziquantel, with shortcomings including treatment failure, reinfection, and emergence of …
praziquantel, with shortcomings including treatment failure, reinfection, and emergence of …