Radiotherapy (RT), including external beam RT and internal radiation therapy, uses high-
energy ionizing radiation to kill tumor cells. However, ionizing radiation inevitably damages …

Collaborative efforts from the fields of biology, materials science, and engineering are
leading to exciting progress in the development of nanomedicines. Since the targets of many …

The strong dependence on oxygen level, low ultraviolet/visible (UV/vis) light penetration
depth and the extremely short lifetime of reactive oxygen species (ROS) are the major …

Highly nitrogen-doped carbon dots (N-CDs) are prepared by the pyrolysis of konjac flour
under mild conditions followed with a simple extraction by ethanol and water. The N-CDs …

Soft fluorescent nanomaterials have attracted recent attention as imaging agents for
biological applications, because they provide the advantages of good biocompatibility, high …

Background Combination of chemotherapy and immune checkpoint inhibitor therapy has
greatly improved the anticancer effect on multiple malignancies. However, the efficiency on …

Temperature dynamics reflect the physiological conditions of cells and organisms.
Mitochondria regulate the temperature dynamics in living cells as they oxidize the …

Understanding the interactions of nanoparticles (NPs) with cells and how these interactions
influence their cellular uptake is essential to exploring the biomedical applications of NPs …

A multifunctional enveloped nanodevice based on mesoporous silica nanoparticle (MSN)
was delicately designed for subcellular co-delivery of drug and therapeutic peptide to tumor …

Well-developed mitochondria-targeted nanocarriers for function regulation are highly
desirable. Numerous studies have been conducted on the treatment of mitochondria-related …