Child and adolescent patients may display mental health concerns within some contexts and
not others (eg, home vs. school). Thus, understanding the specific contexts in which patients …

Heart rate variability (HRV) in individuals with autism spectrum disorders (ASD) has been
investigated in some studies but the procedures and results vary. We conducted a …

Objective: To evaluate how distinct presentations of anxiety symptoms and intellectual
impairment influence the measurement and estimated rate of clinically significant anxiety in …

The aim of the current study was to meta-analytically examine whether anxiety levels in
children with autism spectrum disorders (ASD) are elevated. A total of 83 articles were …

Abstract The Na–K–2Cl cotransporter NKCC1 and the neuron-specific K–Cl cotransporter
KCC2 are considered attractive CNS drug targets because altered neuronal chloride …

Clinicians working with youth with ASD are encouraged to routinely screen for anxiety. Until
further data are available, clinical judgment is needed when prescribing treatments …

Individuals with autism experience substantially higher rates of mood problems compared to
the general population, which contribute to reduced quality of life and increased mortality …

Increasing evidence indicates that brain inflammation is involved in the pathogenesis of
neuropsychiatric diseases. Mast cells (MCs) are located perivascularly close to neurons and …

Individuals with autism spectrum disorder (ASD) may exhibit chronic autonomic nervous
system (ANS) hyperarousal (eg, lower respiratory sinus arrhythmia and higher heart rate) …

Objective: The prevalence of abnormal behavioural responses to a variety of stimuli among
individuals with autism has led researchers to examine whether physiological reactivity (PR) …