Studying non-covalent drug–DNA interactions
Drug–DNA interactions have been extensively studied in the recent past. Various
techniques have been employed to decipher these interactions. DNA is a major target for a …
techniques have been employed to decipher these interactions. DNA is a major target for a …
Synthesis and characterization of two new mixed‐ligand Cu (II) complexes of a tridentate NN'O type Schiff base ligand and N‐donor heterocyclic co‐ligands: In vitro …
Two new mixed‐ligand complexes with general formula [Cu (SB)(L')] ClO4 (1 and 2) were
synthesized and characterized by different spectroscopic and analytical techniques …
synthesized and characterized by different spectroscopic and analytical techniques …
Synthesis and characterization of novel copper (II) complexes as potential drug candidates against SARS-CoV-2 main protease
S Kumar, M Choudhary - New Journal of Chemistry, 2022 - pubs.rsc.org
Two novel copper (II) Schiff base complexes,[Cu (L1) 2](1) and [Cu (L2)(CH3OH)(Cl)](2) of
[(Z)-(5-chloro-2-((3, 5-dichloro-2-hydroxybenzylidene) amino) phenyl)(phenyl) methanone …
[(Z)-(5-chloro-2-((3, 5-dichloro-2-hydroxybenzylidene) amino) phenyl)(phenyl) methanone …
Octahedral copper (ii)-diimine complexes of triethylenetetramine: Effect of stereochemical fluxionality and ligand hydrophobicity on Cu II/Cu I redox, DNA binding and …
M Sharma, M Ganeshpandian, M Majumder… - Dalton …, 2020 - pubs.rsc.org
Octahedral copper (II) complexes of the type [Cu (trien)(diimine)](ClO4) 2 (1–4), where trien
is triethylenetetramine and diimine is 2, 2′-bipyridine (1), 1, 10-phenanthroline (2), 5, 6 …
is triethylenetetramine and diimine is 2, 2′-bipyridine (1), 1, 10-phenanthroline (2), 5, 6 …
Novel 4-quinoline-thiosemicarbazone derivatives: Synthesis, antiproliferative activity, in vitro and in silico biomacromolecule interaction studies and topoisomerase …
AG Ribeiro, SMV de Almeida, JF de Oliveira… - European Journal of …, 2019 - Elsevier
Abstract Twelve 2-(quinolin-4-ylmethylene) hydrazinecarbothioamide derivatives were
synthetized and their biological properties were investigated, among which, the ability to …
synthetized and their biological properties were investigated, among which, the ability to …
Biologically active Cu (II), Co (II), Ni (II) and Zn (II) complexes of pyrimidine derivative Schiff base: DNA binding, antioxidant, antibacterial and in vitro anticancer studies
A new pyrimidine derivative Schiff base ligand (HL)[HL= 2-(4, 6-dimethylpyrimidin-2-ylimino)
methyl)-4-nitrophenol] and its metal (II) complexes [CuL 2](1),[CoL 2](2),[NiL 2](3) and [ZnL …
methyl)-4-nitrophenol] and its metal (II) complexes [CuL 2](1),[CoL 2](2),[NiL 2](3) and [ZnL …
Novel indole-thiazole and indole-thiazolidinone derivatives as DNA groove binders
JEF Alves, JF de Oliveira, TRC de Lima Souza… - International Journal of …, 2021 - Elsevier
In this study, we report the synthesis of eight novel indole-thiazole and indole-thiazolidinone
derivatives, as well as their ability to interact with DNA, analysed through the UV–vis …
derivatives, as well as their ability to interact with DNA, analysed through the UV–vis …
Fluorescent mixed ligand copper (II) complexes of anthracene-appended Schiff bases: studies on DNA binding, nuclease activity and cytotoxicity
P Jaividhya, M Ganeshpandian, R Dhivya… - Dalton …, 2015 - pubs.rsc.org
A series of mixed ligand copper (II) complexes of the type [Cu (L)(phen)(ACN)](ClO4) 21–5,
where L is a bidentate Schiff base ligand (N1-(anthracen-10-ylmethylene)-N2-methylethane …
where L is a bidentate Schiff base ligand (N1-(anthracen-10-ylmethylene)-N2-methylethane …
Mixed-ligand copper (II)-phenolate complexes: structure and studies on DNA/protein binding profiles, DNA cleavage, molecular docking and cytotoxicity
Copper (II) complexes with simple and mixed ligands,[Cu (L)(ClO4)](1) and [Cu (L)(diimine)]
ClO4 (2–4)[where L is 4-chloro-2-((2-(phenylthio) phenylimino) methyl) phenol and diimine …
ClO4 (2–4)[where L is 4-chloro-2-((2-(phenylthio) phenylimino) methyl) phenol and diimine …
Catalytic performance of nickel (II) complexes bearing 1, 10-phenanthroline based ligands in homogeneous ethylene oligomerization
GE Bekmukhamedov, AV Sukhov, AM Kuchkaev… - Polyhedron, 2022 - Elsevier
A comparative study of catalytic activity of nickel (II) complexes bearing 1, 10-phenanthroline
(phen) based ligands in homogeneous ethylene oligomerization process has been …
(phen) based ligands in homogeneous ethylene oligomerization process has been …