The molecular conversations of sarcomas: exosomal non-coding RNAs in tumor's biology and their translational prospects

M Luongo, P Laurenziello, G Cesta, AM Bochicchio… - Molecular Cancer, 2024 - Springer
Exosomes mediate cell-to-cell crosstalk involving a variety of biomolecules through an
intricate signaling network. In recent years, the pivotal role of exosomes and their non …

Hepatitis B Virus and microRNAs: A Bioinformatics Approach

V Zulian, G Fiscon, P Paci, AR Garbuglia - International Journal of …, 2023 - mdpi.com
In recent decades, microRNAs (miRNAs) have emerged as key regulators of gene
expression, and the identification of viral miRNAs (v-miRNAs) within some viruses, including …

Low circulating levels of miR-17 and miR-126-3p are associated with increased mortality risk in geriatric hospitalized patients affected by cardiovascular multimorbidity

F Marchegiani, R Recchioni, M Di Rosa, F Piacenza… - GeroScience, 2024 - Springer
MultiMorbidity (MM), defined as the co-occurrence of two or more chronic conditions, is
associated with poorer health outcomes, such as recurrent hospital readmission and …

miRTarBase 2025: updates to the collection of experimentally validated microRNA–target interactions

S Cui, S Yu, HY Huang, YCD Lin, Y Huang… - Nucleic Acids …, 2024 - academic.oup.com
MicroRNAs (miRNAs) are small non-coding RNAs (18–26 nucleotides) that regulate gene
expression by interacting with target mRNAs, affecting various physiological and …

miR-34a/TAN1/CREB Axis Engages in Alleviating Oligodendrocyte Trophic Factor-Induced Myelin Repair Function and Astrocyte-Dependent Neuroinflammation in …

Y Liu, XK Meng, W Shao, Y Liu, C Tang, S Deng… - Neurochemical …, 2024 - Springer
Reduced myelin stability observed in the early stages of Alzheimer's disease leads to spatial
learning and memory impairment. Exercise has been shown to protect nerves, reduce the …

Machine learning-based integration identifies the ferroptosis hub genes in nonalcoholic steatohepatitis

L Dai, W Yuan, R Jiang, Z Zhan, L Zhang, X Xu… - Lipids in Health and …, 2024 - Springer
Background Ferroptosis, is characterized by lipid peroxidation of fatty acids in the presence
of iron ions, which leads to cell apoptosis. This leads to the disruption of metabolic …

microRNA Expression Profile in Obesity-Induced Kidney Disease Driven by High-Fat Diet in Mice

À Eritja, M Caus, T Belmonte, D de Gonzalo-Calvo… - Nutrients, 2024 - mdpi.com
Obesity is one of the main causes of chronic kidney disease; however, the precise molecular
mechanisms leading to the onset of kidney injury and dysfunction in obesity-associated …

PanomiR: a systems biology framework for analysis of multi-pathway targeting by miRNAs

P Naderi Yeganeh, YY Teo, D Karagkouni… - Briefings in …, 2023 - academic.oup.com
Charting microRNA (miRNA) regulation across pathways is key to characterizing their
function. Yet, no method currently exists that can quantify how miRNAs regulate multiple …

Associations between human milk EV-miRNAs and oligosaccharide concentrations in human milk

EA Holzhausen, WB Patterson, BH Wong… - Frontiers in …, 2024 - frontiersin.org
Introduction Human milk contains human milk oligosaccharides (HMOs) and microRNAs
(miRNAs), which are key bioactive components. HMOs are indigestible carbohydrates that …

Evaluating the performance of multi-omics integration: a thyroid toxicity case study

S Canzler, K Schubert, UE Rolle-Kampczyk… - Archives of …, 2024 - Springer
Multi-omics data integration has been repeatedly discussed as the way forward to more
comprehensively cover the molecular responses of cells or organisms to chemical exposure …