[HTML][HTML] Zoonoses under our noses

AR Cross, VM Baldwin, S Roy, AE Essex-Lopresti… - Microbes and …, 2019 - Elsevier
One Health is an effective approach for the management of zoonotic disease in humans,
animals and environments. Examples of the management of bacterial zoonoses in Europe …

[HTML][HTML] Coxiella burnetii: international pathogen of mystery

AL Dragan, DE Voth - Microbes and infection, 2020 - Elsevier
Coxiella burnetii is an intracellular bacterium that causes acute and chronic Q fever. This
unique pathogen has been historically challenging to study due to obstacles in genetically …

[HTML][HTML] Recent Advances on the Innate Immune Response to Coxiella burnetii

G Sireci, GD Badami, D Di Liberto, V Blanda… - Frontiers in Cellular …, 2021 - frontiersin.org
Coxiella burnetii is an obligate intracellular Gram-negative bacterium and the causative
agent of a worldwide zoonosis known as Q fever. The pathogen invades monocytes and …

Contributions of lipopolysaccharide and the type IVB secretion system to Coxiella burnetii vaccine efficacy and reactogenicity

CM Long, PA Beare, DC Cockrell, J Fintzi… - npj Vaccines, 2021 - nature.com
Coxiella burnetii is the bacterial causative agent of the zoonosis Q fever. The current human
Q fever vaccine, Q-VAX®, is a fixed, whole cell vaccine (WCV) licensed solely for use in …

Genome-wide epitope mapping across multiple host species reveals significant diversity in antibody responses to Coxiella burnetii vaccination and infection

E Bach, SF Fitzgerald, SE Williams-MacDonald… - Frontiers in …, 2023 - frontiersin.org
Coxiella burnetii is an important zoonotic bacterial pathogen of global importance, causing
the disease Q fever in a wide range of animal hosts. Ruminant livestock, in particular sheep …

Efficacy of Phase I and Phase II Coxiella burnetii Bacterin Vaccines in a Pregnant Ewe Challenge Model

SE Williams-Macdonald, M Mitchell, D Frew… - Vaccines, 2023 - mdpi.com
The bacterium Coxiella burnetii can cause the disease Q-fever in a wide range of animal
hosts. Ruminants, including sheep, are thought to play a pivotal role in the transmission of C …

Promiscuous Coxiella burnetii CD4 Epitope Clusters Associated With Human Recall Responses Are Candidates for a Novel T-Cell Targeted Multi-Epitope Q Fever …

A Scholzen, G Richard, L Moise, LA Baeten… - Frontiers in …, 2019 - frontiersin.org
Coxiella burnetii, the causative agent of Q fever, is a Gram-negative intracellular bacterium
transmitted via aerosol. Regulatory approval of the Australian whole-cell vaccine Q-VAX® in …

Evaluation of a Human T Cell-Targeted Multi-Epitope Vaccine for Q Fever in Animal Models of Coxiella burnetii Immunity

AE Sluder, S Raju Paul, L Moise, C Dold… - Frontiers in …, 2022 - frontiersin.org
T cell-mediated immunity plays a central role in the control and clearance of intracellular
Coxiella burnetii infection, which can cause Q fever. Therefore, we aimed to develop a novel …

Tuning subunit vaccines with novel TLR triagonist adjuvants to generate protective immune responses against Coxiella burnetii

AP Gilkes, TJ Albin, S Manna, M Supnet… - The Journal of …, 2020 - journals.aai.org
Coxiella burnetii is an obligate intracellular bacterium and the causative agent of Q fever. C.
burnetii is considered a potential bioterrorism agent because of its low infectious dose; …

Q fever–immune responses and novel vaccine strategies

P Redden, K Parker, S Henderson, P Fourie… - Future …, 2023 - Taylor & Francis
Q fever is a zoonotic disease caused by the bacterium Coxiella burnetii. It is an occupational
risk for employees of animal industries and is associated with contact with wildlife and …