Kinesin superfamily motor proteins and intracellular transport
Intracellular transport is fundamental for cellular function, survival and morphogenesis.
Kinesin superfamily proteins (also known as KIFs) are important molecular motors that …
Kinesin superfamily proteins (also known as KIFs) are important molecular motors that …
Analysis of the kinesin superfamily: insights into structure and function
H Miki, Y Okada, N Hirokawa - Trends in cell biology, 2005 - cell.com
Kinesin superfamily proteins (KIFs) are key players or 'hub'proteins in the intracellular
transport system, which is essential for cellular function and morphology. The KIF …
transport system, which is essential for cellular function and morphology. The KIF …
Molecular motors and mechanisms of directional transport in neurons
N Hirokawa, R Takemura - Nature Reviews Neuroscience, 2005 - nature.com
Intracellular transport is fundamental for neuronal morphogenesis, function and survival.
Many proteins are selectively transported to either axons or dendrites. In addition, some …
Many proteins are selectively transported to either axons or dendrites. In addition, some …
Intracellular transport and kinesin superfamily proteins, KIFs: structure, function, and dynamics
N Hirokawa, Y Noda - Physiological reviews, 2008 - journals.physiology.org
Various molecular cell biology and molecular genetic approaches have indicated significant
roles for kinesin superfamily proteins (KIFs) in intracellular transport and have shown that …
roles for kinesin superfamily proteins (KIFs) in intracellular transport and have shown that …
Integrated regulation of motor-driven organelle transport by scaffolding proteins
M Fu, ELF Holzbaur - Trends in cell biology, 2014 - cell.com
Intracellular trafficking pathways, including endocytosis, autophagy, and secretion, rely on
directed organelle transport driven by the opposing microtubule motor proteins kinesin and …
directed organelle transport driven by the opposing microtubule motor proteins kinesin and …
Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules
The cargo that the molecular motor kinesin moves along microtubules has been elusive. We
searched for binding partners of the COOH terminus of kinesin light chain, which contains …
searched for binding partners of the COOH terminus of kinesin light chain, which contains …
Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I
A Kamal, GB Stokin, Z Yang, CH Xia, LSB Goldstein - Neuron, 2000 - cell.com
We analyzed the mechanism of axonal transport of the amyloid precursor protein (APP),
which plays a major role in the development of Alzheimer's disease. Coimmunoprecipitation …
which plays a major role in the development of Alzheimer's disease. Coimmunoprecipitation …
Single-molecule analysis of kinesin motility reveals regulation by the cargo-binding tail domain
DS Friedman, RD Vale - Nature cell biology, 1999 - nature.com
Conventional kinesin transports membranes along microtubules in vivo, but the majority of
cellular kinesin is unattached to cargo. The motility of non-cargo-bound, soluble kinesin may …
cellular kinesin is unattached to cargo. The motility of non-cargo-bound, soluble kinesin may …
Kinesin superfamily: roles in breast cancer, patient prognosis and therapeutics
AJ Lucanus, GW Yip - Oncogene, 2018 - nature.com
Breast cancer pathobiology is known to be influenced by the differential expression of a
group of proteins called the kinesin superfamily (KIFs), which is instrumental in the …
group of proteins called the kinesin superfamily (KIFs), which is instrumental in the …
p120 catenin associates with kinesin and facilitates the transport of cadherin–catenin complexes to intercellular junctions
p120 catenin (p120) is a component of adherens junctions and has been implicated in
regulating cadherin-based cell adhesion as well as the activity of Rho small GTPases, but its …
regulating cadherin-based cell adhesion as well as the activity of Rho small GTPases, but its …