[HTML][HTML] Making PI3K superfamily enzymes run faster
Abstract The phosphoinositide 3-kinase (PI3K) superfamily includes lipid kinases (PI3Ks
and type III PI4Ks) and a group of PI3K-like Ser/Thr protein kinases (PIKKs: mTOR, ATM …
and type III PI4Ks) and a group of PI3K-like Ser/Thr protein kinases (PIKKs: mTOR, ATM …
Switching Residues: A Platform for the Synthesis of Fidaxomicin Antibiotics
E Jung, T Griesser, J Costafrolaz… - Angewandte …, 2024 - Wiley Online Library
Peripheral modification is often the main approach to optimize natural products for improved
biological activity or desired physicochemical properties. This procedure inevitably …
biological activity or desired physicochemical properties. This procedure inevitably …