Direct compaction: An update of materials, trouble-shooting, and application

Z Li, LJ Zhao, X Lin, L Shen, Y Feng - International Journal of …, 2017 - Elsevier
Direct compaction (DC) is the preferred choice for tablet manufacturing; however, only less
than 20% of active pharmaceutical ingredients could be compacted via DC as its high …

Comparative Evaluation of the Powder and Tableting Properties of Regular and Direct Compression Hypromellose from Different Vendors

N Mawla, M Alshafiee, J Gamble, M Tobyn, L Liu… - Pharmaceutics, 2023 - mdpi.com
Hypromellose, a widely used polymer in the pharmaceutical industry, is available in several
grades, depending on the percentage of substitution of the methoxyl and hydroxypropyl …

[HTML][HTML] Evaluation of Affinisol® HPMC polymers for direct compression process applications

P Khatri, P Katikaneni, D Desai, T Minko - Journal of Drug Delivery Science …, 2018 - Elsevier
Affinisol®(Hydroxypropylmethyl cellulose) polymers with low glass-transition temperature
are usually processed by Melt Extrusion and show better compressibility at lower …

Mannitol-coated hydroxypropyl methylcellulose as an alternative directly compressible controlled release excipient

CYX Kang, WC Foo, KH Lam, KT Chow, YS Lui… - International journal of …, 2024 - Elsevier
One of the most common forms of controlled release technology for oral drug delivery
comprises an active ingredient dispersed in a hydrophilic matrix forming polymer such as …

An investigation into the influence of process parameters and formulation variables on compaction properties of liquisolid systems

I Aleksić, I German Ilić, S Cvijić, J Parojčić - AAPS PharmSciTech, 2020 - Springer
Liquisolid technology, as a promising approach for bioavailability enhancement, has
received increasing attention in recent years. However, literature reports addressing the …

Preparation of Gastro-retentive Tablets Employing Controlled Superporous Networks for Improved Drug Bioavailability

TN Le, J Her, T Sim, CE Jung, JK Kang, KT Oh - AAPS PharmSciTech, 2020 - Springer
The development of an oral formulation that ensures increased bioavailability of drugs is a
great challenge for pharmaceutical scientists. Among many oral formulation systems, a drug …

[HTML][HTML] Engineered food supplement excipients from bitter cassava for minimisation of cassava processing waste in environment

KS Tumwesigye, E O'Brien, JC Oliveira, A Crean… - Future Foods, 2020 - Elsevier
Unchecked large-scale rudimentary upstream (sub-merged and solid state) fermentation
processes of bitter cassava roots into alcohol have often contributed significantly to …

Mucoadhesive sustained-release tablets for vaginal delivery of Curcuma comosa extracts: Preparation and characterization

P Tunpanich, E Limpongsa, T Pongjanyakul… - Journal of Drug Delivery …, 2019 - Elsevier
The objectives of this study were to prepare and characterize the mucoadhesive vaginal
tablets of Curcuma comosa (C. comosa) extract for local delivery of the active …

Formulation and in vitro evaluation of effervescent bilayer floating controlled release tablets of clarithromycin and famotidine

M Alam, KU Shah, KA Khan, A Nawaz… - Research Journal of …, 2021 - indianjournals.com
The development of floating tablets with required buoyancy, lag time, and controlling release
behaviour of drugs at target site is truly interesting and challenging task for researchers …

High-molecular-weight hypromellose from three different suppliers: effects of compression speed, tableting equipment, and moisture on the compaction

P Grdešič, A Paudel, I German Ilić - AAPS PharmSciTech, 2020 - Springer
Use of higher tableting speeds is gaining increasing importance for pharmaceutical industry.
There is a profound lack of new studies of mechanical properties of hypromellose, and none …