FGFs, heparan sulfate and FGFRs: complex interactions essential for development
DM Ornitz - Bioessays, 2000 - Wiley Online Library
Fibroblast growth factors (FGFs) comprise a large family of developmental and physiological
signaling molecules. All FGFs have a high affinity for the glycosaminoglycan heparin and for …
signaling molecules. All FGFs have a high affinity for the glycosaminoglycan heparin and for …
The roles of FGFs in the early development of vertebrate limbs
GR Martin - Genes & development, 1998 - genesdev.cshlp.org
''Fibroblast growth factor''(FGF) was first identified 25 years ago as a mitogenic activity in
pituitary extracts (Armelin 1973; Gospodarowicz 1974). This modest observation …
pituitary extracts (Armelin 1973; Gospodarowicz 1974). This modest observation …
[HTML][HTML] Cytonemes: cellular processes that project to the principal signaling center in Drosophila imaginal discs
FA Ramírez-Weber, TB Kornberg - Cell, 1999 - cell.com
Wing imaginal disc cells in Drosophila develop by using information received from a
signaling center associated with the anterior/posterior compartment border. We show here …
signaling center associated with the anterior/posterior compartment border. We show here …
Nanoplastic at environmentally relevant concentrations induces toxicity across multiple generations associated with inhibition in germline G protein-coupled receptor …
J Wu, Y Shao, X Hua, Y Wang, D Wang - Chemosphere, 2024 - Elsevier
Nanoplastics at environmentally relevant concentrations (ERCs) could cause
transgenerational toxicity on organisms. Caenorhabditis elegans is an important model for …
transgenerational toxicity on organisms. Caenorhabditis elegans is an important model for …
Bmp4 and Fgf10 play opposing roles during lung bud morphogenesis
Morphogenesis of the mouse lung involves reciprocal interactions between the epithelial
endoderm and the surrounding mesenchyme, leading to an invariant early pattern of …
endoderm and the surrounding mesenchyme, leading to an invariant early pattern of …
A real-time biosensor for ERK activity reveals signaling dynamics during C. elegans cell fate specification
Kinase translocation reporters (KTRs) are genetically encoded fluorescent activity sensors
that convert kinase activity into a nucleocytoplasmic shuttling equilibrium for visualizing …
that convert kinase activity into a nucleocytoplasmic shuttling equilibrium for visualizing …
[HTML][HTML] The immunoglobulin superfamily protein SYG-1 determines the location of specific synapses in C. elegans
K Shen, CI Bargmann - Cell, 2003 - cell.com
During nervous system development, neurons form reproducible synapses onto specific
targets. Here, we analyze the development of stereotyped synapses of the C. elegans HSNL …
targets. Here, we analyze the development of stereotyped synapses of the C. elegans HSNL …
Crosstalk Between the EGFR and LIN-12/Notch Pathways in C. elegans Vulval Development
AS Yoo, C Bais, I Greenwald - Science, 2004 - science.org
The Caenorhabditis elegans vulva is an important paradigm for cell-cell interactions in
animal development. The fates of six vulval precursor cells are patterned through the action …
animal development. The fates of six vulval precursor cells are patterned through the action …
[HTML][HTML] Synaptic specificity is generated by the synaptic guidepost protein SYG-2 and its receptor, SYG-1
K Shen, RD Fetter, CI Bargmann - Cell, 2004 - cell.com
Synaptic connections in the nervous system are directed onto specific cellular and
subcellular targets. Synaptic guidepost cells in the C. elegans vulval epithelium drive …
subcellular targets. Synaptic guidepost cells in the C. elegans vulval epithelium drive …
Developmental regulation of a cyclin-dependent kinase inhibitor controls postembryonic cell cycle progression in Caenorhabditis elegans
Y Hong, R Roy, V Ambros - Development, 1998 - journals.biologists.com
ABSTRACT C. elegans cki-1 encodes a member of the CIP/KIP family of cyclin-dependent
kinase inhibitors, and functions to link postembryonic developmental programs to cell cycle …
kinase inhibitors, and functions to link postembryonic developmental programs to cell cycle …