Maternal immune activation and neuroinflammation in human neurodevelopmental disorders
Maternal health during pregnancy plays a major role in shaping health and disease risks in
the offspring. The maternal immune activation hypothesis proposes that inflammatory …
the offspring. The maternal immune activation hypothesis proposes that inflammatory …
IL-6 and IL-8: an overview of their roles in healthy and pathological pregnancies
A Vilotić, M Nacka-Aleksić, A Pirković… - International journal of …, 2022 - mdpi.com
Interleukin-6 (IL-6) is an acknowledged inflammatory cytokine with a pleiotropic action,
mediating innate and adaptive immunity and multiple physiological processes, including …
mediating innate and adaptive immunity and multiple physiological processes, including …
Neuroinflammation and oxidative stress in the pathogenesis of autism spectrum disorder
N Usui, H Kobayashi, S Shimada - International Journal of Molecular …, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder (NDD) characterized by
impairments in social communication, repetitive behaviors, restricted interests, and …
impairments in social communication, repetitive behaviors, restricted interests, and …
Prenatal interleukin 6 elevation increases glutamatergic synapse density and disrupts hippocampal connectivity in offspring
F Mirabella, G Desiato, S Mancinelli, G Fossati… - Immunity, 2021 - cell.com
Early prenatal inflammatory conditions are thought to be a risk factor for different
neurodevelopmental disorders. Maternal interleukin-6 (IL-6) elevation during pregnancy …
neurodevelopmental disorders. Maternal interleukin-6 (IL-6) elevation during pregnancy …
Sex differences in autism spectrum disorder: diagnostic, neurobiological, and behavioral features
A Napolitano, S Schiavi, P La Rosa… - Frontiers in …, 2022 - frontiersin.org
Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder with a
worldwide prevalence of about 1%, characterized by impairments in social interaction …
worldwide prevalence of about 1%, characterized by impairments in social interaction …
[HTML][HTML] Microbiota modulate behavioral and physiological abnormalities associated with neurodevelopmental disorders
Neurodevelopmental disorders, including autism spectrum disorder (ASD), are defined by
core behavioral impairments; however, subsets of individuals display a spectrum of …
core behavioral impairments; however, subsets of individuals display a spectrum of …
The fetal origins of mental illness
BJS Al-Haddad, E Oler, B Armistead… - American journal of …, 2019 - Elsevier
The impact of infections and inflammation during pregnancy on the developing fetal brain
remains incompletely defined, with important clinical and research gaps. Although the …
remains incompletely defined, with important clinical and research gaps. Although the …
The impact of systemic inflammation on neurodevelopment
Inflammatory mediators affect the brain during development. Neurodevelopmental disorders
such as autism spectrum disorders, cognitive impairment, cerebral palsy, epilepsy, and …
such as autism spectrum disorders, cognitive impairment, cerebral palsy, epilepsy, and …
Epigenetic and transgenerational reprogramming of brain development
TL Bale - Nature Reviews Neuroscience, 2015 - nature.com
Neurodevelopmental programming—the implementation of the genetic and epigenetic
blueprints that guide and coordinate normal brain development—requires tight regulation of …
blueprints that guide and coordinate normal brain development—requires tight regulation of …
Oxidative stress and immune system dysfunction in autism spectrum disorders
L Pangrazzi, L Balasco, Y Bozzi - International journal of molecular …, 2020 - mdpi.com
Autism Spectrum Disorders (ASDs) represent a group of neurodevelopmental disorders
associated with social and behavioral impairments. Although dysfunctions in several …
associated with social and behavioral impairments. Although dysfunctions in several …