Computational methods in glaucoma research: current status and future outlook
MJ Kim, CA Martin, J Kim, MM Jablonski - Molecular Aspects of Medicine, 2023 - Elsevier
Advancements in computational techniques have transformed glaucoma research, providing
a deeper understanding of genetics, disease mechanisms, and potential therapeutic targets …
a deeper understanding of genetics, disease mechanisms, and potential therapeutic targets …
[HTML][HTML] Advancements in Contemporary Pharmacological Innovation: Mechanistic Insights and Emerging Trends in Drug Discovery and Development
S Majumder, GK Panigrahi - Intelligent Pharmacy, 2024 - Elsevier
Developing a new drug and bringing it to the market is a complex and time-consuming
process that involves multiple phases of drug discovery and development. However, recent …
process that involves multiple phases of drug discovery and development. However, recent …
Identification of DprE1 inhibitors for tuberculosis through integrated in-silico approaches
Abstract Decaprenylphosphoryl-β-D-ribose-2′-epimerase (DprE1), a crucial enzyme in the
process of arabinogalactan and lipoarabinomannan biosynthesis, has become the target of …
process of arabinogalactan and lipoarabinomannan biosynthesis, has become the target of …
Estrogen receptor alpha (ER-α) antagonistic activity of phytoconstituents from Potentilla atrosanguinea and Potentilla fulgens in breast cancer
The Potentilla genus has long been used traditionally as food and a folklore medicine. In the
present study, aerial parts of two Potentilla species, Potentilla fulgens and Potentilla …
present study, aerial parts of two Potentilla species, Potentilla fulgens and Potentilla …
[HTML][HTML] In Silico Discovery of a Novel PI3Kδ Inhibitor Incorporating 3, 5, 7-Trihydroxychroman-4-one Targeting Diffuse Large B-Cell Lymphoma
W Jia, J Liu, X Cheng, X Li, Y Ma - International Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Diffuse large B-cell lymphoma (DLBCL) is the most common lymphoma, and it is highly
aggressive and heterogeneous. Targeted therapy is still the main treatment method used in …
aggressive and heterogeneous. Targeted therapy is still the main treatment method used in …
Computational-guided approach for identification of PI3K alpha inhibitor in the treatment of hepatocellular carcinoma by virtual screening and water map analysis
Hepatocellular carcinoma (HCC) is one of the most deadly disorders, with a relative survival
rate of 36% in the last 5 years. After an extensive literature survey and pathophysiology …
rate of 36% in the last 5 years. After an extensive literature survey and pathophysiology …