Overview of the current procedures in synthesis of heparin saccharides

S Zhao, T Zhang, Y Kan, H Li, J Li - Carbohydrate Polymers, 2024 - Elsevier
Natural heparin, a glycosaminoglycan consisting of repeating hexuronic acid and
glucosamine linked by 1→ 4 glycosidic bonds, is the most widely used anticoagulant. To …

Automated Synthesis of Algal Fucoidan Oligosaccharides

CJ Crawford, M Schultz-Johansen… - Journal of the …, 2024 - ACS Publications
Fucoidan, a sulfated polysaccharide found in algae, plays a central role in marine carbon
sequestration and exhibits a wide array of bioactivities. However, the molecular diversity and …

Adaptable synthesis of chondroitin sulfate disaccharide subtypes preprogrammed for regiospecific O-sulfation

H Wootton, S Berry, E Ferguson, C Mahon, G Miller - 2024 - chemrxiv.org
A divergent synthetic route to chondroitin sulfate (CS) disaccharide precursors, including
rarer subtypes such as CS-D, has been developed. From common intermediates, a series of …