A spotlight on the diagnostic methods of a fatal disease Visceral Leishmaniasis
Leishmania donovani (a causative agent of visceral leishmaniasis) poses a serious health
threat to the human population which is fatal if left untreated. The life cycle of Leishmania …
threat to the human population which is fatal if left untreated. The life cycle of Leishmania …
Intravacuolar pathogens hijack host extracellular vesicle biogenesis to secrete virulence factors
A Gioseffi, MJ Edelmann, PE Kima - Frontiers in Immunology, 2021 - frontiersin.org
Extracellular vesicles (EVs) have garnered significant interest in recent years due to their
contributions to cell-to-cell communication and disease processes. EVs are composed of a …
contributions to cell-to-cell communication and disease processes. EVs are composed of a …
Leishmania-infected macrophages release extracellular vesicles that can promote lesion development
Leishmania donovani infection of macrophages results in quantitative and qualitative
changes in the protein profile of extracellular vesicles (EVs) released by the infected host …
changes in the protein profile of extracellular vesicles (EVs) released by the infected host …
Characterization and proteomic analysis of plasma EVs recovered from healthy and diseased dogs with canine leishmaniosis
S Esteves, C Lima, I Costa, H Osório… - International Journal of …, 2023 - mdpi.com
Dogs are highly valued companions and work animals that are susceptible to many life-
threatening conditions such as canine leishmaniosis (CanL). Plasma-derived extracellular …
threatening conditions such as canine leishmaniosis (CanL). Plasma-derived extracellular …
Circulating immune complexes levels correlate with the progression of canine leishmaniosis in naturally infected dogs
N Parody, C Cacheiro-Llaguno, C Osuna… - Veterinary …, 2019 - Elsevier
Dogs are the main domestic reservoir of Leishmania infantum, and in cases of uncontrolled
infection, a strong humoral immune response is elicited, which is inefficient against the …
infection, a strong humoral immune response is elicited, which is inefficient against the …
Amphotericin B nano-assemblies circumvent intrinsic toxicity and ensure superior protection in experimental visceral leishmaniasis with feeble toxic manifestation
In spite of its high effectiveness in the treatment of both leishmaniasis as well as a range of
fungal infections, the free form of the polyene antibiotic amphotericin B (AmB) does not …
fungal infections, the free form of the polyene antibiotic amphotericin B (AmB) does not …
Rapid Determination of Vitamin D3 in Aquatic Products by Polypyrrole-Coated Magnetic Nanoparticles Extraction Coupled with High-Performance Liquid …
X Liu, R Song, R Wei - Nanomaterials, 2022 - mdpi.com
A method using polypyrrole-coated Fe3O4 (Fe3O4@ PPy composites) based extraction
coupled with high performance liquid chromatography was developed for adsorption and …
coupled with high performance liquid chromatography was developed for adsorption and …
Screening diagnostic candidates from Leishmania infantum proteins for human visceral leishmaniasis using an immunoproteomics approach
DP Lage, F Ludolf, PC Silveira, AS Machado… - Parasitology, 2019 - cambridge.org
There is no suitable vaccine against human visceral leishmaniasis (VL) and available drugs
are toxic and/or present high cost. In this context, diagnostic tools should be improved for …
are toxic and/or present high cost. In this context, diagnostic tools should be improved for …
A link between circulating immune complexes and acute kidney injury in human visceral leishmaniasis
G Corrêa-Castro, ML Silva-Freitas, L de Paula… - Scientific Reports, 2024 - nature.com
Visceral leishmaniasis (VL) is an infectious disease caused by Leishmania infantum.
Clinically, VL evolves with systemic impairment, immunosuppression and hyperactivation …
Clinically, VL evolves with systemic impairment, immunosuppression and hyperactivation …
Leishmaniasis: Current Trends in Microbiology and Pharmacology
Leishmaniasis is a neglected tropical disease infecting the world's poorest populations in
over 90 countries throughout Asia, Africa, the Middle East, and Central and South America …
over 90 countries throughout Asia, Africa, the Middle East, and Central and South America …