Vascular calcification: New insights into endothelial cells

C Yuan, L Ni, C Zhang, X Hu, X Wu - Microvascular Research, 2021 - Elsevier
Vascular calcification, a common pathological basis of vascular disease, is caused by
various diseases and is an independent risk factor for cardiovascular events. Therefore …

Immune responses in cardiac repair and regeneration: a comparative point of view

SL Lai, R Marín-Juez, DYR Stainier - Cellular and Molecular Life Sciences, 2019 - Springer
Immediately after cardiac injury, the immune system plays major roles in repair and
regeneration as it becomes involved in a number of processes including damage …

Human engineered heart tissue patches remuscularize the injured heart in a dose-dependent manner

E Querdel, M Reinsch, L Castro, D Köse, A Bähr… - Circulation, 2021 - Am Heart Assoc
Background: Human engineered heart tissue (EHT) transplantation represents a potential
regenerative strategy for patients with heart failure and has been successful in preclinical …

Molecular atlas of postnatal mouse heart development

V Talman, J Teppo, P Pöhö, P Movahedi… - Journal of the …, 2018 - Am Heart Assoc
Background The molecular mechanisms mediating postnatal loss of cardiac regeneration in
mammals are not fully understood. We aimed to provide an integrated resource of mRNA …

New treatment methods for myocardial infarction

B Sun, L Wang, W Guo, S Chen, Y Ma… - Frontiers in …, 2023 - frontiersin.org
For a long time, cardiovascular clinicians have focused their research on coronary
atherosclerotic cardiovascular disease and acute myocardial infarction due to their high …

Cardiomyocyte proliferation from fetal-to adult-and from normal-to hypertrophy and failing hearts

SP Bishop, J Zhang, L Ye - Biology, 2022 - mdpi.com
Simple Summary Death from injury to the heart from a variety of causes remains a major
cause of mortality worldwide. The cardiomyocyte, the major contracting cell of the heart, is …

[HTML][HTML] piRNA-6426 increases DNMT3B-mediated SOAT1 methylation and improves heart failure

N Zhong, X Nong, J Diao, G Yang - Aging (Albany NY), 2022 - ncbi.nlm.nih.gov
Purpose: Previous studies found that piRNAs could participate in disease progression by
regulating DNA methylation, but there are few reports on their roles in heart failure (HF) …

Targeting ACSL1 promotes cardiomyocyte proliferation and cardiac regeneration

Y Li, M Yang, J Tan, C Shen, S Deng, X Fu, S Gao, H Li… - Life Sciences, 2022 - Elsevier
Background Neonatal hearts have considerable regenerative potential within 7 days post
birth (P7), but the rate of regeneration is extremely low after P7. Interestingly, lipid …

Diversity of cells and signals in the cardiovascular system

E Grandi, MF Navedo, JJ Saucerman… - The Journal of …, 2023 - Wiley Online Library
This white paper is the outcome of the seventh UC Davis Cardiovascular Research
Symposium on Systems Approach to Understanding Cardiovascular Disease and …

Gene expression variability in human and chimpanzee populations share common determinants

BJ Fair, LE Blake, A Sarkar, BJ Pavlovic, C Cuevas… - Elife, 2020 - elifesciences.org
Inter-individual variation in gene expression has been shown to be heritable and is often
associated with differences in disease susceptibility between individuals. Many studies …