Simple Summary Zebrafish is a crucial in vivo model for lung cancer research and is widely
employed in studies focusing on cancer proliferation, metastasis, and angiogenesis. It plays …

Leukemia is a type of blood cancer characterized by high genetic heterogeneity and fatality.
While chemotherapy remains the primary form of treatment for leukemia, its effectiveness …

The LAMMER kinase in eukaryotes is a well-conserved dual-specificity kinase. Aspergillus
species cause a wide spectrum of diseases called aspergillosis in humans, depending on …

The crosstalk between hematopoietic lineages is important for developmental
hematopoiesis. However, the role of primitive red blood cells (RBCs) in the formation of …

Local adaptation is critical in speciation and evolution, yet comprehensive studies on
proximate and ultimate causes of local adaptation are generally scarce. Here, we integrated …

The response sensitivity to toxic substances is the most concerned performance of animal
model in chemical risk assessment. Casper (mitfa w2/w2; mpv17 a9/a9), a transparent …

Marine natural products are increasingly utilized in nutrition, cosmetics, and medicine,
garnering significant attention from researchers globally. With the expansion of marine …

血脑屏障(BBB) 是中枢神经血管单元的重要结构, 通过紧密连接及转运蛋白阻止神经毒性物质与
病原体入侵, 维护中枢神经系统内环境稳定. 相较于体外模型, 理想的动物模型可更好地模拟BBB …

Primary immunodeficiency (PID) disorders, also commonly referred to as inborn errors of
immunity, are a heterogenous group of human genetic diseases characterized by defects in …

In mammals, T‐cell development depends on the activity of the Foxn1 transcription factor in
the thymic epithelium; mutations in the vertebrate‐specific Foxn1 gene are associated with …