Exploring Peptido‐Nanocomposites in the Context of Amyloid Diseases
N Andrikopoulos, H Tang, Y Wang, X Liang… - Angewandte …, 2024 - Wiley Online Library
Therapeutic peptides are a major class of pharmaceutical drugs owing to their target‐
binding specificity as well as their versatility in inhibiting aberrant protein‐protein …
binding specificity as well as their versatility in inhibiting aberrant protein‐protein …
Navigating the dementia landscape: biomarkers and emerging therapies
S Maheshwari, A Singh - Ageing Research Reviews, 2024 - Elsevier
The field of dementia research has witnessed significant developments in our understanding
of neurodegenerative disorders, with a particular focus on Alzheimer's disease (AD) and …
of neurodegenerative disorders, with a particular focus on Alzheimer's disease (AD) and …
Atomic-thick porous Pd nanosheets with antioxidant enzyme-like activities and photothermal properties for potential Alzheimer's disease treatment
J Ding, W Luo, T Wu, S Cai, ZA Pan, H Li, B Tu, Q Fang… - Nano Today, 2024 - Elsevier
Nanostructure-based regulation on β-amyloid (Aβ) aggregation has shown potential in
Alzheimer's disease (AD) treatment. However, to develop an efficient therapeutic modality …
Alzheimer's disease (AD) treatment. However, to develop an efficient therapeutic modality …
Neuropathogenesis-on-chips for neurodegenerative diseases
S Amartumur, H Nguyen, T Huynh, TS Kim… - Nature …, 2024 - nature.com
Developing diagnostics and treatments for neurodegenerative diseases (NDs) is
challenging due to multifactorial pathogenesis that progresses gradually. Advanced in vitro …
challenging due to multifactorial pathogenesis that progresses gradually. Advanced in vitro …
Cyclin-dependent kinase 5 and neurodegenerative diseases
M Song, Y Qiang, X Zhao, F Song - Molecular Neurobiology, 2024 - Springer
Neurodegenerative diseases are a group of diseases characterized by the progressive loss
of neurons, including Alzheimer's disease, Parkinson's disease, and Amyotrophic lateral …
of neurons, including Alzheimer's disease, Parkinson's disease, and Amyotrophic lateral …
Metformin inhibits nerve growth factor (NGF)-induced sympathetic neuron differentiation through p35/CDK5 inhibition
The authors' previous research has shown the pivotal roles of Cyclin-dependent kinase 5
(CDK5) and its regulatory protein p35 in nerve growth factor (NGF)-induced differentiation of …
(CDK5) and its regulatory protein p35 in nerve growth factor (NGF)-induced differentiation of …
Physiological and pathological roles of the transcriptional kinases CDK12 and CDK13 in the central nervous system
C Pitolli, A Marini, C Sette, V Pagliarini - Cell Death & Differentiation, 2024 - nature.com
The cyclin-dependent kinases 12 (CDK12) and 13 (CDK13) govern several steps of gene
expression, including transcription, RNA processing and translation. The main target of …
expression, including transcription, RNA processing and translation. The main target of …
A Review on Tau Targeting Biomimetics Nano Formulations: Novel Approach for Targeting Alzheimer's Diseases
Central nervous system disorders are prevalent, profoundly debilitating, and poorly
managed. Developing innovative treatments for these conditions, including Alzheimer's …
managed. Developing innovative treatments for these conditions, including Alzheimer's …
An Overview of Recent Advances in the Neuroprotective Potentials of Fisetin against Diverse Insults in Neurological Diseases and the Underlying Signaling Pathways
X Tang, P Deng, Y Jiang, L Zhang, Y He, H Yang - Biomedicines, 2023 - mdpi.com
The nervous system plays a leading role in the regulation of physiological functions and
activities in the body. However, a variety of diseases related to the nervous system have a …
activities in the body. However, a variety of diseases related to the nervous system have a …
Facile synthesis of EGCG modified Au nanoparticles and their inhibitory effects on amyloid protein aggregation
T Wu, Y Zhang, H Li, Z Pan, J Ding, W Zhang… - International Journal of …, 2024 - Elsevier
Preventing β-amyloid (Aβ) peptide aggregation by Au nanoparticles (NPs) is a promising
strategy for the treatment of Alzheimer's disease. However, construction of Au …
strategy for the treatment of Alzheimer's disease. However, construction of Au …