International Union of Basic and Clinical Pharmacology. CX. Classification of receptors for 5-hydroxytryptamine; pharmacology and function
HT receptors expressed throughout the human body are targets for established therapeutics
and various drugs in development. Their diversity of structure and function reflects the …
and various drugs in development. Their diversity of structure and function reflects the …
5-Hydroxytryptamine2-family receptors (5-hydroxytryptamine2A, 5-hydroxytryptamine2B, 5-hydroxytryptamine2C): where structure meets function
BL Roth, DL Willins, K Kristiansen… - Pharmacology & …, 1998 - Elsevier
5-Hydroxytryptamine2 (serotonin2, 5-HT2)-family receptors are important for mediating
many physiological functions, including vascular and nonvascular smooth muscle …
many physiological functions, including vascular and nonvascular smooth muscle …
Quantitative autoradiographic mapping of serotonin receptors in the rat brain. I. Serotonin-1 receptors
A Pazos, JM Palacios - Brain research, 1985 - Elsevier
The distribution of serotonin-1 (5-HT 1) receptors in the rat brain was studied by light
microscopic quantitative autoradiography. Receptors were labeled with [3 H] serotonin (5-[3 …
microscopic quantitative autoradiography. Receptors were labeled with [3 H] serotonin (5-[3 …
Quantitative autoradiographic mapping of serotonin receptors in the rat brain. II. Serotonin-2 receptors
The distribution of serotonin-2 (5-HT 2) receptors in the rat brain was studied by light
microscopic quantitative autoradiography. Receptors were labeled with four ligands:[3 H] …
microscopic quantitative autoradiography. Receptors were labeled with four ligands:[3 H] …
Serotonin receptors in the human brain—IV. Autoradiographic mapping of serotonin-2 receptors
A Pazos, A Probst, JM Palacios - Neuroscience, 1987 - Elsevier
The anatomical distribution of serotonin-2 receptors in the human brain was studied by light
microscopic autoradiography, using [3 H] ketanserin as a ligand. The receptor densities …
microscopic autoradiography, using [3 H] ketanserin as a ligand. The receptor densities …
The pharmacology and distribution of human 5‐hydroxytryptamine2B (5‐HT2b) receptor gene products: comparison with 5‐HT2a and 5‐HT2c receptors
DW Bonhaus, C Bach, A DeSouza… - British journal of …, 1995 - Wiley Online Library
1 Full length clones of the human 5‐HT2B receptor were isolated from human liver, kidney
and pancreas. The cloned human 5‐HT2B receptors had a high degree of homology (∼ …
and pancreas. The cloned human 5‐HT2B receptors had a high degree of homology (∼ …
Serotonin receptors in the human brain—III. Autoradiographic mapping of serotonin-1 receptors
A Pazos, A Probst, JM Palacios - Neuroscience, 1987 - Elsevier
The anatomical distribution of serotonin-1 receptors in human postmortem brain tissue was
studied by quantitative light microscopic autoradiography.[3 H] Serotonin was used to label …
studied by quantitative light microscopic autoradiography.[3 H] Serotonin was used to label …
Identity of inhibitory presynaptic 5-hydroxytryptamine (5-HT) autoreceptors in the rat brain cortex with 5-HT1B binding sites
G Engel, M Göthert, D Hoyer, E Schlicker… - Naunyn-Schmiedeberg's …, 1986 - Springer
In rat brain cortex slices preincubated with [3 H] 5-HT, the potencies of 17 5-HT receptor
agonists to inhibit the electrically evoked 3 H overflow and the affinities of 13 antagonists …
agonists to inhibit the electrically evoked 3 H overflow and the affinities of 13 antagonists …
5-HT2 receptors
JE Leysen - Current Drug Targets-CNS & Neurological …, 2004 - ingentaconnect.com
5-HT2 receptors are G-protein coupled receptors that currently comprise threesubtypes: 5-
HT2A, 5-HT2B and 5-HT2C receptors. The subtypes are related in theirmolecular structure …
HT2A, 5-HT2B and 5-HT2C receptors. The subtypes are related in theirmolecular structure …
Molecular pharmacology of 5-HT1 and 5-HT2 recognition sites in rat and pig brain membranes: radioligand binding studies with [3H] 5-HT,[3H] 8-OH-DPAT,(−)[125I] …
D Hoyer, G Engel, HO Kalkman - European journal of pharmacology, 1985 - Elsevier
The pharmacological characteristics of the binding of [3 H] 8-OH-DPAT ([3 H] 8-hydroxy-2 (di-
n-propylamino) tetralin,[125 I] CYP ((−)[125 I] iodocyanopindolol)(in the presence of 30 μM …
n-propylamino) tetralin,[125 I] CYP ((−)[125 I] iodocyanopindolol)(in the presence of 30 μM …