Alzheimer's disease (AD) genetics may be one of the most prolifically published areas in
medicine and biology. Three early-onset AD genes with causative mutations (APP, PSEN1 …

Attention-deficit/hyperactivity disorder (ADHD) is a highly heritable disorder with a
multifactorial pattern of inheritance. For complex conditions such as this, biologically based …

Pooling genome-wide association studies (GWASs) increases power but also poses
methodological challenges because studies are often heterogeneous. For example …

To provide a definitive linkage map for multiple sclerosis, we have genotyped the Illumina
BeadArray linkage mapping panel (version 4) in a data set of 730 multiplex families of …

We used iterative association mapping to identify a susceptibility gene for age-related
macular degeneration (AMD) on chromosome 10q26, which is one of the most consistently …

Background: Behavioral genetic studies provide strong evidence that attention‐
deficit/hyperactivity disorder (ADHD) has a substantial genetic component. Yet, due to the …

Molecular biologists and geneticists alike now acknowledge that most common human
diseases with a genetic component are likely to have complex etiologies. Yet despite this …

Age-related maculopathy (ARM), or age-related macular degeneration, is one of the most
common causes of visual impairment in the elderly population of developed nations. In a …

The definition of phenotypes for genetic study is a challenging endeavor. Just as we apply
strict quality standards to genotype data, we should expect that phenotypes meet …

A novel phenotyping strategy in schizophrenia, targeting different neurocognitive domains,
neurobehavioral features, and selected personality traits, has allowed us to identify a …