Ageing and chronic degenerative pathologies demonstrate the shared characteristics of
high bioavailability of reactive oxygen species (ROS) and oxidative stress, chronic/persistent …

Tumor-specific, circulating cell-free DNA in liquid biopsies is a promising source of
biomarkers for minimally invasive serial monitoring of treatment responses in cancer …

Through various pathways of cell death, degradation, and regulated extrusion, partial or
complete genomes of various origins (eg, host cells, fetal cells, and infiltrating viruses and …

Proximal tubules energetically internalize and metabolize solutes filtered through glomeruli
but are constantly challenged by foreign substances during the lifespan. Thus, it is critical to …

Autophagy (self-eating) is a conserved cellular degradation process that plays important
roles in maintaining homeostasis and preventing nutritional, metabolic, and infection …

Erythropoiesis is a multi‐step process that involves the differentiation of hematopoietic stem
cells into mature red blood cells (RBCs). This process is regulated by several signaling …

The field of red cell biology is undergoing a quiet revolution. Long assumed to be inert
oxygen carriers, RBCs are emerging as important modulators of the innate immune …

Nicotinic acid adenine dinucleotide phosphate (NAADP) is a second messenger that
releases Ca2+ from acidic organelles through the activation of two-pore channels (TPCs) to …

Human red blood cells (RBC) are highly differentiated cells that have lost all organelles and
most intracellular machineries during their maturation process. RBC are fundamental for the …

The majority of human proteins operate as multimeric complexes with defined compositions
and distinct architectures. How the assembly of these complexes is surveyed and how …