Platelets—blood cells continuously produced from megakaryocytes mainly in the bone
marrow—are implicated not only in haemostasis and arterial thrombosis, but also in other …

Cardiovascular disease remains the main cause of death worldwide. For this reason,
strategies for the primary prevention of atherosclerosis and atherosclerosis-related …

Aim To evaluate the prevalence of peri‐implant diseases and to identify risk/protective
indicators of peri‐implantitis. Materials and Methods Two hundred and forty randomly …

Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can
lead to a variety of clinical outcomes, ranging from the absence of symptoms to severe acute …

Background: Despite the well-established benefits of secondary cardiovascular prevention,
the importance of concurrent medical therapy in clinical trials of coronary revascularization is …

Platelets play a significant role in atherothrombosis. Proprotein convertase subtilisin/kexin
type 9 (PCSK9) is critically involved in the regulation of LDL metabolism and interacts with …

Platelet activation plays a critical role in thrombosis. Inhibition of platelet activation is a
cornerstone in treatment of acute organ ischemia. Platelet ACKR3 surface expression is …

Platelet-leukocyte crosstalk is commonly manifested by reciprocal links between thrombosis
and inflammation. Platelet thrombus acts as a reactive matrix that recruits leukocytes to the …

Anti-platelet drugs reduce arterial thrombosis after plaque rupture and erosion, prevent stent
thrombosis and are used to prevent and treat myocardial infarction and ischaemic stroke …

Novel antiplatelet drugs, including ticagrelor, are being successively introduced into the
therapy of atherothrombotic conditions due to their superiority over a standard combination …