Recent epidemiology studies highlighted the detrimental health effects of exposure to low
dose and low dose rate ionizing radiation (IR): nuclear industry workers studies have shown …

Ionizing radiation (IR) is an ever-present hazard to humans primarily due to its mutagenic,
carcinogenic, and cell killing ability. In addition to causing DNA damage, irradiation initiates …

Purpose: To establish a panel of highly radiation responsive genes suitable for biological
dosimetry and to explore inter-individual variation in response to ionising radiation …

Previous investigations in gene expression changes in blood after radiation exposure have
highlighted its potential to provide biomarkers of exposure. Here, FDXR transcriptional …

Background The capacity to assess environmental inputs to biological phenotypes is limited
by methods that can accurately and quantitatively measure these contributions. One such …

Organisms respond to physical, chemical and biological threats by a potent inflammatory
response, aimed at preserving tissue integrity and restoring tissue homeostasis and …

Elsewhere, we reported that multiple serial in vivo passage of a squamous cell carcinoma
cells (SCC61) concurrent with ionizing radiation (IR) treatment resulted in the selection of …

Abstract Coleman, MA, Yin, E., Peterson, LE, Nelson, D., Sorensen, K., Tucker, JD and
Wyrobek, AJ Low-Dose Irradiation Alters the Transcript Profiles of Human Lymphoblastoid …

Full exploitation of microarray data requires hidden information that cannot be extracted
using current analysis methodologies. We present a new approach, hidden variable …

Radiotherapy remains the mainstay for treatment of various types of human cancer;
however, the clinical efficacy is often limited by radioresistance, in which the underlying …