Clinical application of liquid biopsy in colorectal cancer: detection, prediction, and treatment monitoring

XY Tao, QQ Li, Y Zeng - Molecular Cancer, 2024 - Springer
Colorectal cancer (CRC) is one of the most prevalent malignancies affecting the
gastrointestinal tract and is ranked third among cancers with the highest incidence and …

Predictive performance of cell-free nucleic acid-based multi-cancer early detection tests: a systematic review

E LeeVan, P Pinsky - Clinical Chemistry, 2024 - academic.oup.com
Background Cancer-screening tests that can detect multiple cancer types, or multi-cancer
early detection (MCED) tests, have emerged recently as a potential new tool in decreasing …

A Platelet Reactivity ExpreSsion Score derived from patients with peripheral artery disease predicts cardiovascular risk

JS Berger, MG Cornwell, Y Xia, MA Muller… - Nature …, 2024 - nature.com
Platelets are key mediators of atherothrombosis, yet, limited tools exist to identify individuals
with a hyperreactive platelet phenotype. In this study, we investigate the association of …

Cancer signature ensemble integrating cfDNA methylation, copy number, and fragmentation facilitates multi-cancer early detection

SY Kim, S Jeong, W Lee, Y Jeon, YJ Kim… - … & molecular medicine, 2023 - nature.com
Cell-free DNA (cfDNA) sequencing has demonstrated great potential for early cancer
detection. However, most large-scale studies have focused only on either targeted …

Liquid biopsy: creating opportunities in brain space

R Trivedi, KP Bhat - British journal of cancer, 2023 - nature.com
In recent years, liquid biopsy has emerged as an alternative method to diagnose and
monitor tumors. Compared to classical tissue biopsy procedures, liquid biopsy facilitates the …

Megakaryocyte-and erythroblast-specific cell-free DNA patterns in plasma and platelets reflect thrombopoiesis and erythropoiesis levels

J Moss, R Ben-Ami, E Shai, O Gal-Rosenberg… - Nature …, 2023 - nature.com
Circulating cell-free DNA (cfDNA) fragments are a biological analyte with extensive utility in
diagnostic medicine. Understanding the source of cfDNA and mechanisms of release is …

Platelet RNA enables accurate detection of ovarian cancer: an intercontinental, biomarker identification study

Y Gao, CJ Liu, HY Li, XM Xiong, GL Li… - Protein & …, 2023 - academic.oup.com
Platelets are reprogrammed by cancer via a process called education, which favors cancer
development. The transcriptional profile of tumor-educated platelets (TEPs) is skewed and …

Tumor educated platelet: the novel BioSource for cancer detection

S Ding, X Dong, X Song - Cancer Cell International, 2023 - Springer
Platelets, involved in the whole process of tumorigenesis and development, constantly
absorb and enrich tumor-specific substances in the circulation during their life span, thus …

[HTML][HTML] Current and future applications of liquid biopsy in non-small-cell lung cancer—a narrative review

B Tomasik, M Skrzypski, M Bieńkowski… - Translational Lung …, 2023 - ncbi.nlm.nih.gov
Current and future applications of liquid biopsy in non-small-cell lung cancer—a narrative
review - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage …

Dissecting order amidst chaos of programmed cell deaths: construction of a diagnostic model for KIRC using transcriptomic information in blood-derived exosomes …

C Wang, Y He, J Zheng, X Wang, S Chen - Frontiers in Immunology, 2023 - frontiersin.org
Background Kidney renal clear cell carcinoma (KIRC) is the most frequently diagnosed
subtype of renal cell carcinoma (RCC); however, the pathogenesis and diagnostic …