Hair is a defining feature of mammals and has critical functions, including protection,
production of sebum, apocrine sweat and pheromones, social and sexual interactions …

Hair follicles, which are connected to sebaceous glands in the skin, undergo cyclic periods
of regeneration, degeneration, and rest throughout adult life in mammals. The crucial …

Behavioral genetics in dogs has focused on modern breeds, which are isolated subgroups
with distinctive physical and, purportedly, behavioral characteristics. We interrogated breed …

Chronic, sustained exposure to stressors can profoundly affect tissue homeostasis, although
the mechanisms by which these changes occur are largely unknown. Here we report that the …

Piloerection (goosebumps) requires concerted actions of the hair follicle, the arrector pili
muscle (APM), and the sympathetic nerve, providing a model to study interactions across …

Stem cell activity is subject to non-cell-autonomous regulation from the local
microenvironment, or niche. In adaption to varying physiological conditions and the ever …

The dermal papilla (DP) of the hair follicle is both a chemical and physical niche for
epithelial progenitor cells that regenerate the cycling portion of the hair follicle and generate …

A hallmark of aged mesenchymal stem/progenitor cells (MSCs) in bone marrow is the pivot
of differentiation potency from osteoblast to adipocyte coupled with a decrease in self …

The hair follicle (HF) represents a prototypic ectodermal–mesodermal interaction system in
which central questions of modern biology can be studied. A unique feature of these stem …

Cell fate transitions are essential for specification of stem cells and their niches, but the
precise timing and sequence of molecular events during embryonic development are largely …