Why miltefosine—a life-saving drug for leishmaniasis—is unavailable to people who need it the most

T Sunyoto, J Potet, M Boelaert - BMJ global health, 2018 - gh.bmj.com
Miltefosine, the only oral drug approved for the treatment of leishmaniasis—a parasitic
disease transmitted by sandflies—is considered as a success story of research and …

Towards elimination of visceral leishmaniasis in the Indian subcontinent—Translating research to practice to public health

S Hirve, A Kroeger, G Matlashewski… - PLoS Neglected …, 2017 - journals.plos.org
Background The decade following the Regional Strategic Framework for Visceral
Leishmaniasis (VL) elimination in 2005 has shown compelling progress in the reduction of …

The global procurement landscape of leishmaniasis medicines

HL Choi, S Jain, JA Ruiz Postigo… - PLoS Neglected …, 2021 - journals.plos.org
Ensuring access to essential medicines for leishmaniasis control is challenging, as
leishmaniasis is a very small and unattractive market for pharmaceutical industry …

Failure of miltefosine treatment for visceral leishmaniasis in children and men in South-East Asia

B Ostyn, E Hasker, TPC Dorlo, S Rijal, S Sundar… - PloS one, 2014 - journals.plos.org
Background High frequency of relapse in miltefosine-treated visceral leishmaniasis (VL)
patients in India and Nepal followed up for twelve months. Objective To identify …

Assessment of the impact of implementation research on the Visceral Leishmaniasis (VL) elimination efforts in Nepal

AB Joshi, MR Banjara, S Chuke… - PLOS Neglected …, 2023 - journals.plos.org
Nepal, Bangladesh, and India signed a Memorandum of Understanding (MoU) in 2005 to
eliminate visceral leishmaniasis (VL) as a public health problem from the Indian …

Visceral leishmaniasis diagnosis and reporting delays as an obstacle to timely response actions in Nepal and India

JP Boettcher, Y Siwakoti, A Milojkovic… - BMC infectious …, 2015 - Springer
Background To eliminate visceral leishmaniasis (VL) in India and Nepal, challenges of VL
diagnosis, treatment and reporting need to be identified. Recent data indicate that VL is …

Barriers and facilitators of visceral leishmaniasis case management in the Amhara Region, Northwest Ethiopia: an exploratory qualitative study

YM Gelaw, JP Gangneux, GD Alene… - BMC Public Health, 2024 - Springer
Background Visceral leishmaniasis (VL) is among the world's most serious public health
threats, causing immense human suffering and death. In Ethiopia, little is known about the …

Visceral Leishmaniasis in pregnancy and vertical transmission: A systematic literature review on the therapeutic orphans

P Dahal, S Singh-Phulgenda, BJ Maguire… - PLoS neglected …, 2021 - journals.plos.org
Background Reports on the occurrence and outcome of Visceral Leishmaniasis (VL) in
pregnant women is rare in published literature. The occurrence of VL in pregnancy is not …

Silver and nitrate oppositely modulate antimony susceptibility through aquaglyceroporin 1 in Leishmania (Viannia) species

JM Andrade, EH Baba… - Antimicrobial Agents …, 2016 - Am Soc Microbiol
Antimony (Sb) resistance in leishmaniasis chemotherapy has become one of the major
challenges to the control of this spreading worldwide public health problem. Since the …

Introducing single dose liposomal amphotericin B for the treatment of visceral leishmaniasis in rural bangladesh: feasibility and acceptance to patients and health staff

EM Maintz, M Hassan, MM Huda… - Journal of tropical …, 2014 - Wiley Online Library
Background. For the treatment of visceral leishmaniasis in Bangladesh, single dose
liposomal amphotericin B (ambisome) is supposed to be the safest and most effective …