Today the pharmacological possibilities of treating cancer are expanding and as a result, life
expectancy is increasing against the background of chemotherapy and supportive treatment …

Doxorubicin (DOX), as a kind of chemotherapy agent with remarkable therapeutic effect, can
be used to treat diverse malignant tumors clinically. Dose-dependent cardiotoxicity is the …

The main adverse effect of doxorubicin is cardiotoxicity. Oxidative stress and apoptosis
induction have been suggested as mechanisms involved in its cardiotoxicity. In this study …

Simple Summary There is growing interest in identifying the effects of antidiabetic agents on
cancer risk, progression, and anti-cancer treatment due to the long-term use of these …

According to the World Health Organization, the neoplasm is one of the main reasons for
morbidity and mortality worldwide. At the same time, application of cytostatic drugs like an …

Even while accelerated cardiomyocyte apoptosis is one of the primary causes of cardiac
damage, the underlying mechanism is still mostly unknown. In addition to examining …

Introduction and objectives The current study evaluates the effect of chelidonic acid on
doxorubicin-induced cardiac toxicity. Chelidonic acid (CA) is a natural pyran-skeleton …

Background Cardiovascular complications, arising after anthracycline chemotherapy, cause
a significant deterioration in the life quality and expectancy of those patients who were …

Abstract Activation transcription factor 3 (ATF3), a member of the ATF/cyclic adenosine
monophosphate response element binding family, can be induced by a variety of stresses …

Diabetes mellitus (DM) is a significant risk factor for various cancers, with the impact of anti-
diabetic therapies on cancer progression differing across malignancies. Among these …