Parkinson's disease as a result of aging
M Rodriguez, C Rodriguez‐Sabate, I Morales… - Aging cell, 2015 - Wiley Online Library
It is generally considered that Parkinson's disease is induced by specific agents that
degenerate a clearly defined population of dopaminergic neurons. Data commented in this …
degenerate a clearly defined population of dopaminergic neurons. Data commented in this …
The neuroprotective effects of intermittent fasting on brain aging and neurodegenerative diseases via regulating mitochondrial function
Y Zhao, M Jia, W Chen, Z Liu - Free Radical Biology and Medicine, 2022 - Elsevier
Intermittent fasting (IF) has been studied for its effects on lifespan and the prevention or
delay of age-related diseases upon the regulation of metabolic pathways. Mitochondria …
delay of age-related diseases upon the regulation of metabolic pathways. Mitochondria …
Neurodegenerative diseases: multifactorial conformational diseases and their therapeutic interventions
Neurodegenerative diseases are multifactorial debilitating disorders of the nervous system
that affect approximately 30 millionindividuals worldwide. Neurodegenerative diseases such …
that affect approximately 30 millionindividuals worldwide. Neurodegenerative diseases such …
Fasting in mood disorders: neurobiology and effectiveness. A review of the literature
Clinicians have found that fasting was frequently accompanied by an increased level of
vigilance and a mood improvement, a subjective feeling of well-being, and sometimes of …
vigilance and a mood improvement, a subjective feeling of well-being, and sometimes of …
Preconditioning provides neuroprotection in models of CNS disease: paradigms and clinical significance
Preconditioning is a phenomenon in which brief episodes of a sublethal insult induce robust
protection against subsequent lethal injuries. Preconditioning has been observed in multiple …
protection against subsequent lethal injuries. Preconditioning has been observed in multiple …
[HTML][HTML] Evaluating the beneficial effects of dietary restrictions: A framework for precision nutrigeroscience
Dietary restriction (DR) has long been viewed as the most robust nongenetic means to
extend lifespan and healthspan. Many aging-associated mechanisms are nutrient …
extend lifespan and healthspan. Many aging-associated mechanisms are nutrient …
Dietary factors in the etiology of Parkinson's disease
Parkinson's disease (PD) is the second most common neurodegenerative disorder. The
majority of cases do not arise from purely genetic factors, implicating an important role of …
majority of cases do not arise from purely genetic factors, implicating an important role of …
A dietary regimen of caloric restriction or pharmacological activation of SIRT1 to delay the onset of neurodegeneration
Caloric restriction (CR) is a dietary regimen known to promote lifespan by slowing down the
occurrence of age-dependent diseases. The greatest risk factor for neurodegeneration in the …
occurrence of age-dependent diseases. The greatest risk factor for neurodegeneration in the …
Genetics, Life Span, Health Span, and the Aging Process in Caenorhabditis elegans
HA Tissenbaum - Journals of Gerontology Series A: Biomedical …, 2012 - academic.oup.com
As a tool for measuring the aging process, life span has been invaluable in dissecting the
genes that modulate longevity. Studies over the past few decades have identified several …
genes that modulate longevity. Studies over the past few decades have identified several …
Mitochondrial dynamics: orchestrating the journey to advanced age
AK Biala, R Dhingra, LA Kirshenbaum - Journal of molecular and cellular …, 2015 - Elsevier
Aging is a degenerative process that unfortunately is an inevitable part of life and risk factor
for cardiovascular disease including heart failure. Among the several theories purported to …
for cardiovascular disease including heart failure. Among the several theories purported to …