The American Psychiatric Association Practice Guideline for the Treatment of Patients With
Schizophrenia seeks to reduce these substantial psychosocial and public health …

The management of acute extrapyramidal effects (EPEs) induced by antipsychotic drugs is
reviewed. EPEs associated with antipsychotics include acute dystonias …

Acetylcholine (ACh) signaling is critical for central nervous function and is known to be
abnormal in schizophrenia (SZ), a chronic neuropsychiatric disorder in which cognitive …

It is often implied that antipsychotic-induced extrapyramidal side-effects are irrelevant to
modern psychiatric therapeutics, rendered historic by newer, better treatments. This myth …

BACKGROUND: Amantadine, an aliphatic primary amine with complex actions on
neurotransmitter systems in the basal ganglia, is approved for treating Parkinson's disease …

Most patients on neuroleptic therapy experience extrapyramidal symptoms in one form or
another during treatment. While the risk of extrapyramidal symptoms appears diminished …

This chapter describes the various drugs used to treat extrapyramidal symptoms (EPS). The
unique properties of chlorpromazine and other similarly active agents in ameliorating …

Acute extrapyramidal syndromes (EPS), including dystonia, parkinsonism, and akathisia, are
associated with the use of virtually all neuroleptic agents. They may be alleviated by …

Previous antiparkinson drug withdrawal studies involving white subjects have yielded
inconclusive findings, whereas there is a paucity of data concerning Asian patients. A …

Twelve stabilized chronic schizophrenic outpatients receiving maintenance treatment with
fluphenazine decanoate plus anticholinergic antiparkinsonian drugs underwent two …