Kinetochores are large protein assemblies that connect chromosomes to microtubules of the
mitotic and meiotic spindles in order to distribute the replicated genome from a mother cell to …

Kinetochores are molecular machines that power chromosome segregation during the
mitotic and meiotic cell divisions of all eukaryotes. Aristotle explains how we think we have …

This study determined whether morphokinetic variables between aneuploid and euploid
embryos differ as a potential aid to select euploid embryos for transfer. Following …

In eukaryotes, accurate chromosome segregation in mitosis and meiosis maintains genome
stability and prevents aneuploidy. Kinetochores are large protein complexes that, by …

Chromosomes are carriers of genetic material and their accurate transfer from a mother cell
to its two daughters during cell division is of paramount importance for life. Kinetochores are …

To faithfully segregate chromosomes during vertebrate mitosis, kinetochore–microtubule
interactions must be restricted to a single site on each chromosome. Prior work on pair-wise …

The propagation of all organisms depends on the accurate and orderly segregation of
chromosomes in mitosis and meiosis. Budding yeast has long served as an outstanding …

To position the mitotic spindle within the cell, dynamic plus ends of astral microtubules are
pulled by membrane-associated cortical force-generating machinery. However, in contrast to …

Kinetochores connect centromeric nucleosomes with mitotic-spindle microtubules through
conserved, cross-interacting protein subassemblies. In budding yeast, the heterotetrameric …

Highlights•Kinetochores, large macromolecular assemblies, link chromosome to spindle
microtubules.•Kinetochores are crucially required for accurate chromosome segregation in …