A complete section is devoted to each of these fields. In the first two sections, concepts that
are crucial in radiation physics and radiobiology are reviewed in depth. The third section …

Treatment of cancer using radiation can be significantly compromised by the development of
severe acute and late damage to normal tissue. Treatments that either reduce the risk and …

Radiation-induced complications in bone and cartilage are of increasing concern due to
potential long-term effects in cancer survivors. Healthy articular cartilage may be exposed to …

Particle therapy (PT) that utilizes protons and carbon ions offers a promising way to reduce
the side effects of radiation oncology, especially in pediatric patients. To investigate the …

Articular cartilage is a specialized connective tissue, predominately composed of water,
collagen, and proteoglycans, that provides a smooth, lubricated surface for articulation in …

Purpose: Little is known regarding radiation effects on adult articular (joint) cartilage, though
joint damage has been reported following cancer treatment or occupational exposures. The …

Here, we show that Src homology 2-domain-containing inositol 5′-phosphatase 1 (SHIP1)
is required for the efficient development of osteoblasts from mesenchymal stem cells (MSCs) …

The purpose of this study was to determine the differential effects of therapeutic X‐radiation
on constituent bone cells relative to the pediatric tumor cells: Ewing's sarcoma of bone and …

Radiation is the energy and irradiation is the process. There is a noun form and a verb form
for each. The x-ray tube and the isotope radiate energy, and the patient is being irradiated …

Purpose: Premature musculoskeletal joint failure is a major source of morbidity among
childhood cancer survivors. Radiation effects on synovial joint tissues of the skeleton are …