Clinical updates in adult immune thrombocytopenia

MP Lambert, TB Gernsheimer - Blood, The Journal of the …, 2017 - ashpublications.org
Immune thrombocytopenia (ITP) occurs in 2 to 4/100 000 adults and results in variable
bleeding symptoms and thrombocytopenia. In the last decade, changes in our …

Splenectomy for immune thrombocytopenia: down but not out

S Chaturvedi, DM Arnold… - Blood, The Journal of the …, 2018 - ashpublications.org
Splenectomy is an effective therapy for steroid-refractory or dependent immune
thrombocytopenia (ITP). With the advent of medical alternatives such as rituximab and …

Primary immune thrombocytopenia: novel insights into pathophysiology and disease management

A Singh, G Uzun, T Bakchoul - Journal of Clinical Medicine, 2021 - mdpi.com
Immune thrombocytopenia (ITP) is an autoimmune disorder defined by a significantly
reduced number of platelets in blood circulation. Due to low levels of platelets, ITP is …

Pediatric ITP: is it different from adult ITP?

JM Despotovic, AB Grimes - Hematology 2014, the American …, 2018 - ashpublications.org
Immune thrombocytopenia (ITP) has historically been thought to occur in 2 distinct forms:
childhood ITP and adult ITP. This division is based largely on the presumption that …

Splenectomy for primary immune thrombocytopenia revisited in the era of thrombopoietin receptor agonists: new insights for an old treatment

A Mageau, L Terriou, M Ebbo… - American Journal of …, 2022 - Wiley Online Library
Although splenectomy is still considered the most effective curative treatment for immune
thrombocytopenia (ITP), its use has significantly declined in the last decade, especially since …

Refractory primary immune thrombocytopenia (ITP): current clinical challenges and therapeutic perspectives

N Vianelli, G Auteri, F Buccisano, V Carrai… - Annals of …, 2022 - Springer
Chronic primary immune thrombocytopenia (ITP) can today benefit from multiple therapeutic
approaches with proven clinical efficacy, including rituximab, thrombopoietin receptor …

[HTML][HTML] Laparoscopic splenectomy: Current concepts

EP Misiakos, G Bagias, T Liakakos… - World journal of …, 2017 - ncbi.nlm.nih.gov
Since early 1990's, when it was inaugurally introduced, laparoscopic splenectomy has been
performed with excellent results in terms of intraoperative and postoperative complications …

Treatment efficacy for adult persistent immune thrombocytopenia: a systematic review and network meta‐analysis

T Puavilai, K Thadanipon, S Rattanasiri… - British journal of …, 2020 - Wiley Online Library
Persistent immune thrombocytopenia (ITP) patients require second‐line treatments, for
which information on clinical outcomes are lacking. A systematic review and network meta …

Splenectomy outcomes in immune cytopenias: Treatment outcomes and determinants of response

OD Ogbue, W Bahaj, T Kewan, R Ahmed… - Journal of Internal …, 2024 - Wiley Online Library
Background Splenectomy is commonly used to treat refractory immune–mediated cytopenia,
but there are no established factors that are associated with response to the procedure …

Eltrombopag in immune thrombocytopenia: efficacy review and update on drug safety

JR Gonzalez-Porras… - Therapeutic Advances in …, 2018 - journals.sagepub.com
Immune thrombocytopenia (ITP) is an autoimmune disorder that induces a decrease in the
number of circulating platelets due to spleen destruction and inability of megakaryocytes to …