[HTML][HTML] Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease
Inflammation occurs as a result of exposure of tissues and organs to harmful stimuli such as
microbial pathogens, irritants, or toxic cellular components. The primary physical …
microbial pathogens, irritants, or toxic cellular components. The primary physical …
Neuroinflammation in Parkinson's disease: its role in neuronal death and implications for therapeutic intervention
MG Tansey, MS Goldberg - Neurobiology of disease, 2010 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disease, after
Alzheimer's disease. The potential causes of PD remain uncertain, but recent studies …
Alzheimer's disease. The potential causes of PD remain uncertain, but recent studies …
MicroRNA-7 targets Nod-like receptor protein 3 inflammasome to modulate neuroinflammation in the pathogenesis of Parkinson's disease
Y Zhou, M Lu, RH Du, C Qiao, CY Jiang… - Molecular …, 2016 - Springer
Abstract Background α-Synuclein (α-Syn), a pathological hallmark of Parkinson's disease
(PD), has been recognized to induce the production of interleukin-1β in a process that …
(PD), has been recognized to induce the production of interleukin-1β in a process that …
Toll‐like receptor 4 is required for α‐synuclein dependent activation of microglia and astroglia
Alpha‐synucleinopathies (ASP) are neurodegenerative disorders, characterized by
accumulation of misfolded α‐synuclein, selective neuronal loss, and extensive gliosis. It is …
accumulation of misfolded α‐synuclein, selective neuronal loss, and extensive gliosis. It is …
Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression
HM Gao, JS Hong - Trends in immunology, 2008 - cell.com
Neurodegenerative diseases are a group of chronic, progressive disorders characterized by
the gradual loss of neurons in discrete areas of the central nervous system (CNS). The …
the gradual loss of neurons in discrete areas of the central nervous system (CNS). The …
Dietary polyphenols as modulators of brain functions: biological actions and molecular mechanisms underpinning their beneficial effects
D Vauzour - Oxidative medicine and cellular longevity, 2012 - Wiley Online Library
Accumulating evidence suggests that diet and lifestyle can play an important role in delaying
the onset or halting the progression of age‐related health disorders and to improve cognitive …
the onset or halting the progression of age‐related health disorders and to improve cognitive …
Pharmacological inhibition of necroptosis protects from dopaminergic neuronal cell death in Parkinson's disease models
A Iannielli, S Bido, L Folladori, A Segnali, C Cancellieri… - Cell reports, 2018 - cell.com
Dysfunctions in mitochondrial dynamics and metabolism are common pathological
processes associated with Parkinson's disease (PD). It was recently shown that an inherited …
processes associated with Parkinson's disease (PD). It was recently shown that an inherited …
[HTML][HTML] Immune responses in the Parkinson's disease brain
F Weiss, A Labrador-Garrido, N Dzamko… - Neurobiology of …, 2022 - Elsevier
Immune changes occur in all neurodegenerative conditions, but there are significant
differences between diseases. For Parkinson's disease (PD), the immune system …
differences between diseases. For Parkinson's disease (PD), the immune system …
Flavonoids, cognition, and dementia: actions, mechanisms, and potential therapeutic utility for Alzheimer disease
RJ Williams, JPE Spencer - Free Radical Biology and Medicine, 2012 - Elsevier
There is increasing evidence that the consumption of flavonoid-rich foods can beneficially
influence normal cognitive function. In addition, a growing number of flavonoids have been …
influence normal cognitive function. In addition, a growing number of flavonoids have been …
The neuroprotective potential of flavonoids: a multiplicity of effects
D Vauzour, K Vafeiadou, A Rodriguez-Mateos… - Genes & nutrition, 2008 - Springer
Flavonoids exert a multiplicity of neuroprotective actions within the brain, including a
potential to protect neurons against injury induced by neurotoxins, an ability to suppress …
potential to protect neurons against injury induced by neurotoxins, an ability to suppress …