Lipoprotein (a) as a cause of cardiovascular disease: insights from epidemiology, genetics, and biology

BG Nordestgaard, A Langsted - Journal of lipid research, 2016 - ASBMB
Human epidemiologic and genetic evidence using the Mendelian randomization approach
in large-scale studies now strongly supports that elevated lipoprotein (a)[Lp (a)] is a causal …

Apolipoprotein (a) isoforms and the risk of vascular disease: systematic review of 40 studies involving 58,000 participants

S Erqou, A Thompson, E Di Angelantonio… - Journal of the American …, 2010 - jacc.org
Objectives: The purpose of this study was to assess the association of apolipoprotein
(a)(apo [a]) isoforms with cardiovascular disease risk. Background: Although circulating …

Lipoprotein (a) an elusive cardiovascular risk factor

L Berglund, R Ramakrishnan - Arteriosclerosis, thrombosis, and …, 2004 - Am Heart Assoc
Lipoprotein (a)[Lp (a)], is present only in humans, Old World nonhuman primates, and the
European hedgehog. Lp (a) has many properties in common with low-density lipoprotein …

Apolipoprotein (a) size and lipoprotein (a) concentration and future risk of angina pectoris with evidence of severe coronary atherosclerosis in men: The Physicians' …

N Rifai, J Ma, FM Sacks, PM Ridker… - Clinical …, 2004 - academic.oup.com
Background: The relationship of lipoprotein (a)[Lp (a)] concentrations with risk of coronary
heart disease needs clarification, especially for threshold values for increased risk and for …

Adverse effects of danazol prophylaxis on the lipid profiles of patients with hereditary angioedema

G Széplaki, L Varga, S Valentin, M Kleiber… - Journal of allergy and …, 2005 - Elsevier
BACKGROUND: Hereditary angioedema (HAE) is a rare disorder caused by the deficiency
of the C1-inhibitor gene (C1INH). Patients experience recurrent bouts of edema, which can …

Bone vascularization in normal and disease conditions

C Carulli, M Innocenti, ML Brandi - Frontiers in Endocrinology, 2013 - frontiersin.org
Bone vasculature is essential for many processes, such as skeletal development and
growth, bone modeling and remodeling, and healing processes. Endothelium is an integral …

Pentanucleotide TTTTA repeat polymorphism of apolipoprotein (a) gene and plasma lipoprotein (a) are associated with ischemic and hemorrhagic stroke in Chinese …

L Sun, Z Li, H Zhang, A Ma, Y Liao, D Wang, B Zhao… - Stroke, 2003 - Am Heart Assoc
Background and Purpose—It is still inconclusive whether high plasma lipoprotein (a)[Lp (a)]
level is a risk factor for stroke. Small sample size and different ethnic groups and …

Association of polymorphisms and allelic combinations in the tumour necrosis factor-α-complement MHC region with coronary artery disease

C Szalai, G Füst, J Duba, J Kramer, L Romics… - Journal of medical …, 2002 - jmg.bmj.com
MATERIALS AND METHODS We have recruited 59 nuclear families (a total of 214 subjects)
from a hypertension clinic at Taipei Veterans General Hospital, Taiwan. Our study group …

Low molecular weight phenotype of Apo (a) is a risk factor of corticosteroid-induced osteonecrosis of the femoral head after renal transplant.

T Hirata, M Fujioka, KA Takahashi, T Asano… - The Journal of …, 2007 - jrheum.org
OBJECTIVE: Osteonecrosis of the femoral head (ONF) is a necrosis due to disruption of the
blood flow. The disease often occurs in association with corticosteroid treatment. The …

[HTML][HTML] Copy number variation of the Lipoprotein (a)(LPA) gene is associated with coronary artery disease in a southern Han Chinese population

Z Wu, H Sheng, Y Chen, J Tang, Y Liu… - … journal of clinical and …, 2014 - ncbi.nlm.nih.gov
Copy number variations (CNVs), genomic duplication or deletion events occurring at larger
than 1 kb scale, contribute to the complex diseases substantially. Lipoprotein (a)[Lp (a)] is a …