Half a century of amyloids: past, present and future

PC Ke, R Zhou, LC Serpell, R Riek… - Chemical Society …, 2020 - pubs.rsc.org
Amyloid diseases are global epidemics with profound health, social and economic
implications and yet remain without a cure. This dire situation calls for research into the …

Review on Alzheimer's disease: inhibition of amyloid beta and tau tangle formation

H Ashrafian, EH Zadeh, RH Khan - International journal of biological …, 2021 - Elsevier
It is reported that approximately 40 million people are suffering from dementia, globally.
Dementia is a group of symptoms that affect neurons and cause some mental disorders …

Proteostasis of islet amyloid polypeptide: a molecular perspective of risk factors and protective strategies for type II diabetes

D Milardi, E Gazit, SE Radford, Y Xu… - Chemical …, 2021 - ACS Publications
The possible link between hIAPP accumulation and β-cell death in diabetic patients has
inspired numerous studies focusing on amyloid structures and aggregation pathways of this …

Neuroprotective effects of quercetin in Alzheimer's disease

H Khan, H Ullah, M Aschner, WS Cheang, EK Akkol - Biomolecules, 2019 - mdpi.com
Quercetin is a flavonoid with notable pharmacological effects and promising therapeutic
potential. It is widely distributed among plants and found commonly in daily diets …

Effect of resveratrol and pterostilbene on aging and longevity

YR Li, S Li, CC Lin - Biofactors, 2018 - Wiley Online Library
Over the past years, several studies have found that foods rich in polyphenols protect
against age‐related disease, such as atherosclerosis, cardiovascular disease, cancer …

The many faces of α-synuclein: from structure and toxicity to therapeutic target

HA Lashuel, CR Overk, A Oueslati… - Nature Reviews …, 2013 - nature.com
Disorders characterized by α-synuclein (α-syn) accumulation, Lewy body formation and
parkinsonism (and in some cases dementia) are collectively known as Lewy body diseases …

Design, functionalization strategies and biomedical applications of targeted biodegradable/biocompatible polymer-based nanocarriers for drug delivery

J Nicolas, S Mura, D Brambilla, N Mackiewicz… - Chemical Society …, 2013 - pubs.rsc.org
Design and functionalization strategies for multifunctional nanocarriers (eg, nanoparticles,
micelles, polymersomes) based on biodegradable/biocompatible polymers intended to be …

π–π stacking interaction: a nondestructive and facile means in material engineering for bioapplications

T Chen, M Li, J Liu - Crystal Growth & Design, 2018 - ACS Publications
π–π stacking interactions, as a kind of attractive and nondestructive noncovalent interaction,
have been widely explored for the applications in modern chemistry, molecular biology, and …

Implications of peptide assemblies in amyloid diseases

PC Ke, MA Sani, F Ding, A Kakinen, I Javed… - Chemical Society …, 2017 - pubs.rsc.org
Neurodegenerative disorders and type 2 diabetes are global epidemics compromising the
quality of life of millions worldwide, with profound social and economic implications. Despite …

Plant polyphenols: chemical properties, biological activities, and synthesis

S Quideau, D Deffieux… - Angewandte Chemie …, 2011 - Wiley Online Library
Eating five servings of fruits and vegetables per day! This is what is highly recommended
and heavily advertised nowadays to the general public to stay fit and healthy! Drinking green …