The remarkable evolutionary plasticity of coronaviruses by mutation and recombination: insights for the COVID-19 pandemic and the future evolutionary paths of …

GD Amoutzias, M Nikolaidis, E Tryfonopoulou… - Viruses, 2022 - mdpi.com
Coronaviruses (CoVs) constitute a large and diverse subfamily of positive-sense single-
stranded RNA viruses. They are found in many mammals and birds and have great …

Recombination in enteroviruses, a multi-step modular evolutionary process

C Muslin, A Mac Kain, M Bessaud, B Blondel… - Viruses, 2019 - mdpi.com
RNA recombination is a major driving force in the evolution and genetic architecture shaping
of enteroviruses. In particular, intertypic recombination is implicated in the emergence of …

How much reduction of virus is needed for recycled water: A continuous changing need for assessment?

CP Gerba, WQ Betancourt, M Kitajima - Water research, 2017 - Elsevier
To ensure the safety of wastewater reuse for irrigation of food crops and drinking water
pathogenic viruses must be reduced to levels that pose no significant risk. To achieve this …

Current understanding of human enterovirus D68

J Sun, XY Hu, XF Yu - Viruses, 2019 - mdpi.com
Human enterovirus D68 (EV-D68), a member of the species Enterovirus D of the
Picornaviridae family, was first isolated in 1962 in the United States. EV-D68 infection was …

Epidemiology and sequence-based evolutionary analysis of circulating non-polio enteroviruses

DM Brown, Y Zhang, RH Scheuermann - Microorganisms, 2020 - mdpi.com
Enteroviruses (EVs) are positive-sense RNA viruses, with over 50,000 nucleotide
sequences publicly available. While most human infections are typically associated with …

Enteroviral 2B interacts with VDAC3 to regulate reactive oxygen species generation that is essential to viral replication

ML Cheng, CH Wu, KY Chien, CH Lai, GJ Li, YY Liu… - Viruses, 2022 - mdpi.com
Enterovirus (EV) 71 caused episodes of outbreaks in China and Southeast Asia during the
last few decades. We have previously reported that EV71 induces reactive oxygen species …

[HTML][HTML] Large-scale genomic analysis reveals recurrent patterns of intertypic recombination in human enteroviruses

M Nikolaidis, K Mimouli, Z Kyriakopoulou, M Tsimpidis… - Virology, 2019 - Elsevier
Recombination is a driving force for the emergence, evolution and virulence/epidemics of
viruses, comprising the Enterovirus genus of the Picornaviridae family, important for human …

Dissemination of internal ribosomal entry sites (IRES) between viruses by horizontal gene transfer

Y Arhab, AG Bulakhov, TV Pestova, CUT Hellen - Viruses, 2020 - mdpi.com
Members of Picornaviridae and of the Hepacivirus, Pegivirus and Pestivirus genera of
Flaviviridae all contain an internal ribosomal entry site (IRES) in the 5′-untranslated region …

Human pathogenic RNA viruses establish noncompeting lineages by occupying independent niches

P Mutz, ND Rochman, YI Wolf… - Proceedings of the …, 2022 - National Acad Sciences
Many pathogenic viruses are endemic among human populations and can cause a broad
variety of diseases, some potentially leading to devastating pandemics. How virus …

Prevalence and molecular characterizations of enterovirus D68 among children with acute respiratory infection in China between 2012 and 2014

Q Xiao, L Ren, S Zheng, L Wang, X Xie, Y Deng… - Scientific reports, 2015 - nature.com
EV-D68 is associated with respiratory tract infections (RTIs). Since its first isolation, EV-D68
has been detected sporadically. However, the US and Canada have experienced outbreaks …