The research of integrin-targeted anticancer agents has recorded important advancements
in ingenious design of delivery systems, based either on the prodrug approach, or on …

Prior to metastasis, modern therapeutics and surgical intervention can provide a favorable
long-term survival for patients diagnosed with many types of cancers. However, prognosis is …

In the search for new drug-like selective G-quadruplex binders, a bioinspired design focused
on the use of nucleobases as synthons in a multicomponent reaction was herein proved to …

The development of novel therapies increasingly relies on sophisticated delivery systems
that allow the drug or gene expression-modifying agent of interest entry into cells. These …

Targeting of G‐quadruplex‐forming DNA in the BCL2 gene promoter to inhibit the
expression of anti‐apoptotic Bcl‐2 protein is an attractive approach to cancer treatment. So …

The mesenchymal sub-type of triple negative breast cancer (MES-TNBC) has a highly
aggressive behavior and worse prognosis, due to its invasive and stem-like features, that …

Here, silica-coated PbS quantum dots (QDs) with photoluminescence emission properties in
the near-infrared (NIR) region are proposed as potential effective single particle optical …

The critical role of integrins in tumor progression and metastasis has stimulated intense
efforts to identify pharmacological agents that can modulate integrin function. In recent …

Herein, we report the synthesis and biological characterization of the new peptide
ψRGDechi as the first step toward novel-targeted theranostics in melanoma. This …

The ability to modulate angiogenesis by chemical tools has several important applications in
different scientific fields. With the perspective of finding novel proangiogenic molecules, we …