Curcumin is a polyphenol natural product isolated from turmeric, interacting with different
cellular and molecular targets and, consequently, showing a wide range of pharmacological …

Results: Administration of low doses of curcumin (0.1 and 1 µg/ml) could decrease Th17
percentages (p= 0.000 and p= 0.000 compared to control), reduce IL-17A productions (p …

Background Despite advances in general and targeted immunosuppressive therapies,
limiting all mainstay treatment options in refractory systemic lupus erythematosus (SLE) …

Vitamin D deficiency has been associated with pathogenesis of autoimmune diseases
including SLE; however, there were still lack of data about the effects of administration of …

Background. Curcumin contained in Curcuma xanthorrhiza is an immunomodulator that has
similar biological effect as vitamin D. Combination of curcumin and vitamin D3 is expected to …

Abstract Background Systemic Lupus Erythematosus (SLE) is a chronic autoimmune
disease characterized by the presence of autoantibodies against nuclear genes, deposition …

The city of Kupang was assigned as the dirtiest city of number one by the Ministry of
Environment and Forestry in the East Nusa Tenggara Province-Indonesia in the assessment …

Methods Forty-eight female BALB/c mice were divided into a healthy control (HC) and a
pristine-induced (PI) group. SLE was induced by a single 0.5 cc pristane intraperitoneal …

Acupressure is one of physiotherapy by putting pressure and stimulating acupuncture points
(acu points) on the body which aims to stimulate or stimula therapeutic points using the …

Introduction: SLE pathophysiology shifted to a new paradigm which emphasizing the
imbalance between Th17 and Treg. IL-6 is the main cytokine believed as the regulator of the …