Natural products have been an invaluable and useful source of anticancer agents over the
years. Several compounds have been synthesized from natural products by modifying their …

Ethnopharmacological relevance Triple-negative breast cancer (TNBC) has a poorer
prognosis than other subtypes due to its strong invasion and higher risk of distant …

Epithelial-to-mesenchymal transition (EMT) is a self-regulated physiological process
required for tissue repair that, in non-controled conditions may lead to fibrosis …

Recently, patient-derived xenograft (PDX) models of many types of tumors including breast
cancer have emerged as a powerful tool for predicting drug efficacy and for understanding …

Abstract Changes in lifestyle such as physical activity and eating habits have been one of
the main reasons for development of various diseases in modern world, especially cancer …

Simple Summary Wnt has diverse regulatory roles at multiple cellular levels and numerous
targeting points, and aberrant Wnt signaling has crucial roles in carcinogenesis, metastasis …

Breast tumors are heterogeneous and composed of different subpopulation of cells, each
with dynamic roles that can change with stage, site, and microenvironment. Cellular …

WNT10B, a member of the WNT family of secreted glycoproteins, activates the WNT/β-
catenin signaling cascade to control proliferation, stemness, pluripotency, and cell fate …

Triple-negative breast cancer (TNBC) is the most aggressive type of cancer, with a high risk
of death on recurrence. To date, there is a lack of approved targeted agents for the treatment …

BACKGROUND: Ovarian cancer (OC) is the fifth most common type of cancer in women
worldwide. MiR-27a plays an important role in the development of ovarian cancer. However …