Application of phage display for T-cell receptor discovery

ACW Ch'ng, P Lam, M Alassiri, TS Lim - Biotechnology Advances, 2022 - Elsevier
The immune system is tasked to keep our body unharmed and healthy. In the immune
system, B-and T-lymphocytes are the two main components working together to stop and …

Combined in vitro and cell‐based selection display method producing specific binders against IL‐9 receptor in high yields

M Huličiak, L Biedermanová, D Berdár… - The FEBS …, 2023 - Wiley Online Library
We combined cell‐free ribosome display and cell‐based yeast display selection to build
specific protein binders to the extracellular domain of the human interleukin 9 receptor alpha …

Targeting acute myeloid cell surface using a recombinant antibody isolated from whole-cell biopanning of a phage display human scFv antibody library

T Sumphanapai, K Chester, S Sawatnatee, J Yeung… - Medical Oncology, 2022 - Springer
To discover new therapeutic antibodies for treatment of acute myeloid leukemia (AML)
without the requirement of a known antigen, a human single-chain variable fragment (scFv) …

Isolation and Characterization of the Vascular Endothelial Growth Factor Receptor Targeting ScFv Antibody Fragments Derived from Phage Display Technology

H Kazemzadeh, M Bagheri, M Sepehri, E Ebrahimi… - ACS …, 2024 - ACS Publications
Angiogenesis, as a tumor hallmark, plays an important role in the growth and development
of the tumor vasculature system. There is a huge amount of evidence suggesting that the …

[HTML][HTML] 噬菌体抗体库技术在肿瘤治疗中的研究进展及应用

陈晓阳, 安瑞珩, 黄菊, 梁有沣, 张文静, 郝明炫… - 生物工程 …, 2023 - cjb.ijournals.cn
肿瘤是严重威胁人类健康的疾病. 目前肿瘤治疗策略以手术切除, 放化疗, 靶向治疗和免疫治疗为
主. 单克隆抗体药物因具备高效性和低毒性等特点, 逐渐成为肿瘤临床治疗中不可或缺的药物 …

[PDF][PDF] KRT80 expression works as a biomarker and a target for differentiation in gastric cancer

K Shi, H Xue, E Zhao, L Xiao, H Sun, H Zheng - Histol Histopathol, 2024 - hh.um.es
Keratin 80 (KRT80) is a filament protein that participates in cell differentiation and the
integrity of the epithelial barrier. Here, KRT80 expression was higher in gastric cancer …

Bio-assay of the non-amidated progastrin-derived peptide (G17-Gly) using the tailor-made recombinant antibody fragment and phage display method: a biomedical …

D Sadighbayan, MR Tohidkia, T Mehdipour… - Analytical …, 2020 - pubs.rsc.org
In this research, four novel and sensitive immunosensors for electrochemical determination
of G17-Gly were designed based on signal amplification and tailor-made recombinant …

KRT80 expression works as a biomarker and a target for differentiation in gastric cancer

H Xue, HC Zheng - 2024 - digitum.um.es
. Keratin 80 (KRT80) is a filament protein that participates in cell differentiation and the
integrity of the epithelial barrier. Here, KRT80 expression was higher in gastric cancer …

Withaferin A: The Potent Anti-Cancer Agent from Ashwagandha

D Pal, D Kashyap, A Sharma, U Sharma… - Available at SSRN … - papers.ssrn.com
Withania somnifera (Ashwagandha) is a medicinal plant that has been an integral part of
Ayurveda for centuries. It is well documented that components of Withania somnifera have …