Endothelial senescence in vascular diseases: current understanding and future opportunities in senotherapeutics

Y Han, SY Kim - Experimental & Molecular Medicine, 2023 - nature.com
Senescence compromises the essential role that the endothelium plays in maintaining
vascular homeostasis, so promoting endothelial dysfunction and the development of age …

Lycopene in the prevention of cardiovascular diseases

S Przybylska, G Tokarczyk - International Journal of Molecular Sciences, 2022 - mdpi.com
Cardiovascular diseases (CVDs) are the leading cause of human mortality worldwide.
Oxidative stress and inflammation are pathophysiological processes involved in the …

[HTML][HTML] Molecularly targeted nanomedicine enabled by inorganic nanoparticles for atherosclerosis diagnosis and treatment

X Zhang, F Centurion, A Misra, S Patel, Z Gu - Advanced drug delivery …, 2023 - Elsevier
Atherosclerosis, a chronic cardiovascular disease caused by plaque development in
arteries, remains a leading cause of morbidity and mortality. Atherosclerotic plaques are …

[HTML][HTML] Advances in drug delivery to atherosclerosis: Investigating the efficiency of different nanomaterials employed for different type of drugs

B Perera, Y Wu, NT Nguyen, HT Ta - Materials Today Bio, 2023 - Elsevier
Atherosclerosis is the build-up of fatty deposits in the arteries. Atherosclerosis is the main
underlying cause of cardiovascular diseases and the leading cause of global morbidity and …

Advances in the treatment of atherosclerosis with ligand‐modified nanocarriers

X Deng, J Wang, S Yu, S Tan, T Yu, Q Xu, N Chen… - …, 2024 - Wiley Online Library
Atherosclerosis, a chronic disease associated with metabolism, poses a significant risk to
human well‐being. Currently, existing treatments for atherosclerosis lack sufficient efficiency …

Roles of macrophages in atherogenesis

L Farahi, SK Sinha, AJ Lusis - Frontiers in pharmacology, 2021 - frontiersin.org
Atherosclerosis is a chronic inflammatory disease that may ultimately lead to local
proteolysis, plaque rupture, and thrombotic vascular disease, resulting in myocardial …

Self-oxygenation mesoporous MnO2 nanoparticles with ultra-high drug loading capacity for targeted arteriosclerosis therapy

W Sun, Y Xu, Y Yao, J Yue, Z Wu, H Li, G Shen… - Journal of …, 2022 - Springer
Atherosclerosis (AS) is a leading cause of vascular diseases that severely threats the human
health due to the lack of efficient therapeutic methods. During the development and progress …

[HTML][HTML] Natural biopolymers as smart coating materials of mesoporous silica nanoparticles for drug delivery

B Dumontel, V Conejo-Rodríguez, M Vallet-Regí… - Pharmaceutics, 2023 - mdpi.com
In recent years, the functionalization of mesoporous silica nanoparticles (MSNs) with
different types of responsive pore gatekeepers have shown great potential for the …

Recent Progress in in vitro Models for Atherosclerosis Studies

J Chen, X Zhang, R Millican, T Lynd… - Frontiers in …, 2022 - frontiersin.org
Atherosclerosis is the primary cause of hardening and narrowing arteries, leading to
cardiovascular disease accounting for the high mortality in the United States. For developing …

Near-Infrared II Fluorescence Imaging and Image-Guided siRNA Therapy of Atherosclerosis

J Gao, K Yu, Q Luo, M Deng, X Hou… - Journal of medicinal …, 2024 - ACS Publications
Targeting Ca2+/calmodulin-dependent protein kinase γ (CaMKIIγ) in macrophages using
RNAi nanotechnology represents an innovative and promising strategy in the diagnosis and …