▪ Abstract A variety of isoforms of mammalian voltage-gated sodium channels have been
described. Ten genes encoding sodium channel α subunits have been identified, and nine …

The voltage-gated Na+, Ca*+, and K+ channels are responsible for the generation of action
potentials in neurons and other excitable cells. These channels are also involved in cellular …

Voltage-sensitive sodium channels are responsible for the initiation and propagation of the
action potential and therefore are important for neuronal excitability. Complementary DNA …

Although rat brain Nav1. 3 voltage-gated sodium channels have been expressed and
studied in Xenopus oocytes, these channels have not been studied after their expression in …

The expression of sodium channel α-, β1-and β2-subunit mRNAs was examined in adult rat
DRG neurons in dissociated culture at 1 day in vitro and within sections of intact ganglia by …

After transection of their axons within the sciatic nerve, DRG neurons become
hyperexcitable. Recent studies have demonstrated the emergence of a rapidly repriming …

Voltage-gated sodium channels composed of pore-forming α and auxiliary β subunits are
responsible for the rising phase of the action potential in cardiac muscle, but the functional …

Voltage-gated Na+ channels play important functional roles in the generation of electrical
excitability in most vertebrate and invertebrate species. These channels are members of a …

Dorsal root ganglion neurons express a wide repertoire of sodium channels with different
properties. Here, we report the cloning from rat, dorsal root ganglia (DRG), cellular …

Previous studies have shown that transection of the sciatic nerve induces dramatic changes
in sodium currents of axotomized dorsal root ganglion (DRG) neurons, which are paralleled …