TRiC/CCT chaperonin: structure and function
The eukaryotic group II chaperonin TRiC/CCT assists the folding of 10% of cytosolic proteins
including many key structural and regulatory proteins. TRiC plays an essential role in …
including many key structural and regulatory proteins. TRiC plays an essential role in …
Function and regulation of cytosolic molecular chaperone CCT
H Kubota - 2002 - Elsevier
Molecular chaperones are a group of proteins that assists in the folding of newly synthesized
proteins or in the refolding of denatured proteins. The cytosolic chaperonin-containing t …
proteins or in the refolding of denatured proteins. The cytosolic chaperonin-containing t …
Cytosolic chaperonin is up-regulated during cell growth: Preferential expression and binding to tubulin at G1/S transition through early S phase
S Yokota, H Yanagi, T Yura, H Kubota - Journal of Biological Chemistry, 1999 - ASBMB
The chaperonin containing t-complex polypeptide 1 (CCT) is a heterooligomeric molecular
chaperone assisting in the folding of actin, tubulin, and other cytosolic proteins. The …
chaperone assisting in the folding of actin, tubulin, and other cytosolic proteins. The …
The Parkin co-regulated gene product, PACRG, is an evolutionarily conserved axonemal protein that functions in outer-doublet microtubule morphogenesis
HR Dawe, H Farr, N Portman… - Journal of cell …, 2005 - journals.biologists.com
Eukaryotic cilia and flagella are highly conserved structures composed of a canonical 9+ 2
microtubule axoneme. Comparative genomics of flagellated and non-flagellated eukaryotes …
microtubule axoneme. Comparative genomics of flagellated and non-flagellated eukaryotes …
The structure and evolution of eukaryotic chaperonin-containing TCP-1 and its mechanism that folds actin into a protein spring
KR Willison - Biochemical Journal, 2018 - portlandpress.com
Actin is folded to its native state in eukaryotic cytosol by the sequential allosteric mechanism
of the chaperonin-containing TCP-1 (CCT). The CCT machine is a double-ring ATPase built …
of the chaperonin-containing TCP-1 (CCT). The CCT machine is a double-ring ATPase built …
Cloning, characterization and sub-cellular localization of gamma subunit of T-complex protein-1 (chaperonin) from Leishmania donovani
N Kumari, N Goyal - Biochemical and Biophysical Research …, 2012 - Elsevier
T-complex protein-1 (TCP1) complex, a chaperonin class of protein, ubiquitous in all genera
of life, is involved in intracellular assembly and folding of various proteins. The gamma …
of life, is involved in intracellular assembly and folding of various proteins. The gamma …
Subunits of the eukaryotic cytosolic chaperonin CCT do not always behave as components of a uniform hetero-oligomeric particle
A Roobol, MJ Carden - European journal of cell biology, 1999 - Elsevier
The chaperonin CCT is an hetero-oligomeric molecular chaperone complex. Stndies in
yeast suggest each of its eight gene products are required for its major identified functions in …
yeast suggest each of its eight gene products are required for its major identified functions in …
CCTα and CCTδ Chaperonin Subunits Are Essential and Required for Cilia Assembly and Maintenance in Tetrahymena
Background The eukaryotic cytosolic chaperonin CCT is a hetero-oligomeric complex
formed by two rings connected back-to-back, each composed of eight distinct subunits …
formed by two rings connected back-to-back, each composed of eight distinct subunits …
Chaperonin containing T-complex polypeptide subunit eta (CCT-eta) is a specific regulator of fibroblast motility and contractility
Integumentary wounds in mammalian fetuses heal without scar; this scarless wound healing
is intrinsic to fetal tissues and is notable for absence of the contraction seen in postnatal …
is intrinsic to fetal tissues and is notable for absence of the contraction seen in postnatal …
Molecular chaperones in cilia and flagella: implications for protein turnover
RE Stephens, NA Lemieux - Cell motility and the cytoskeleton, 1999 - Wiley Online Library
The mechanisms of protein incorporation and turnover in 9+ 2 ciliary axonemes are not
known. Previous reports of an HSP70‐related protein, first in Chlamydomonas flagella and …
known. Previous reports of an HSP70‐related protein, first in Chlamydomonas flagella and …