[HTML][HTML] Convergent evolution of SARS-CoV-2 XBB lineages on receptor-binding domain 455–456 synergistically enhances antibody evasion and ACE2 binding
F Jian, L Feng, S Yang, Y Yu, L Wang, W Song… - PLoS …, 2023 - journals.plos.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) XBB lineages have
achieved dominance worldwide and keep on evolving. Convergent evolution of XBB …
achieved dominance worldwide and keep on evolving. Convergent evolution of XBB …
[HTML][HTML] Spike deep mutational scanning helps predict success of SARS-CoV-2 clades
B Dadonaite, J Brown, TE McMahon, AG Farrell… - Nature, 2024 - nature.com
SARS-CoV-2 variants acquire mutations in the spike protein that promote immune evasion
and affect other properties that contribute to viral fitness, such as ACE2 receptor binding and …
and affect other properties that contribute to viral fitness, such as ACE2 receptor binding and …
[HTML][HTML] Deep mutational scanning reveals functional constraints and antigenic variability of Lassa virus glycoprotein complex
CR Carr, KHD Crawford, M Murphy, JG Galloway… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Lassa virus is estimated to cause thousands of human deaths per year, primarily due to
spillovers from its natural host, Mastomys rodents. Efforts to create vaccines and antibody …
spillovers from its natural host, Mastomys rodents. Efforts to create vaccines and antibody …
Using high throughput technologies to understand heterogeneous drug response
GE Boyle - 2023 - search.proquest.com
Heterogeneity is an inherent quality of biological systems, and is one of the properties that
facilitates adaptation of organisms to new environments and stimuli. However, the scientific …
facilitates adaptation of organisms to new environments and stimuli. However, the scientific …