Role of toll‐like receptors in modulation of cytokine storm signaling in SARS‐CoV‐2‐induced COVID‐19
M Manik, RK Singh - Journal of medical virology, 2022 - Wiley Online Library
Balanced immune regulation is crucial for recognizing an invading pathogen, its killing, and
elimination. Toll‐like receptors (TLRs) are the key regulators of the innate immune system. It …
elimination. Toll‐like receptors (TLRs) are the key regulators of the innate immune system. It …
Pulmonary surfactant: A mighty thin film
F Possmayer, YY Zuo, RAW Veldhuizen… - Chemical …, 2023 - ACS Publications
Pulmonary surfactant is a critical component of lung function in healthy individuals. It
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …
Persistent SARS‐CoV‐2 infection in patients seemingly recovered from COVID‐19
R Bussani, L Zentilin, R Correa, A Colliva… - The Journal of …, 2023 - Wiley Online Library
SARS‐CoV‐2 infection is clinically heterogeneous, ranging from asymptomatic to deadly. A
few patients with COVID‐19 appear to recover from acute viral infection but nevertheless …
few patients with COVID‐19 appear to recover from acute viral infection but nevertheless …
[HTML][HTML] Epigenome-wide association study of COVID-19 severity with respiratory failure
MC de Moura, V Davalos, L Planas-Serra… - …, 2021 - thelancet.com
Background Patients infected with the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), responsible for the coronavirus disease 2019 (COVID-19), exhibit a wide …
(SARS-CoV-2), responsible for the coronavirus disease 2019 (COVID-19), exhibit a wide …
Complement C3 inhibition in severe COVID-19 using compstatin AMY-101
Complement C3 activation contributes to COVID-19 pathology, and C3 targeting has
emerged as a promising therapeutic strategy. We provide interim data from ITHACA, the first …
emerged as a promising therapeutic strategy. We provide interim data from ITHACA, the first …
[HTML][HTML] COVID19 biomarkers: What did we learn from systematic reviews?
S Semiz - Frontiers in cellular and infection microbiology, 2022 - frontiersin.org
The coronavirus disease 2019 (COVID19) pandemic continues to represent a substantial
public health concern. It can rapidly progress to severe disease, with poor prognosis and a …
public health concern. It can rapidly progress to severe disease, with poor prognosis and a …
[HTML][HTML] The pathological maelstrom of COVID-19 and cardiovascular disease
M Giacca, AM Shah - Nature Cardiovascular Research, 2022 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) is a consequence of infection of the upper
and lower respiratory tract with severe acute respiratory syndrome coronavirus 2 but often …
and lower respiratory tract with severe acute respiratory syndrome coronavirus 2 but often …
[HTML][HTML] Arterial and venous thrombosis complicated in COVID-19: a retrospective single center analysis in Japan
S Oba, T Hosoya, M Amamiya, T Mitsumura… - Frontiers in …, 2021 - frontiersin.org
[Background] Thrombosis is a characteristic complication in Coronavirus disease 2019
(COVID-19). Since coagulopathy has been observed over the entire clinical course …
(COVID-19). Since coagulopathy has been observed over the entire clinical course …
[HTML][HTML] Differences in coagulopathy indices in patients with severe versus non-severe COVID-19: a meta-analysis of 35 studies and 6427 patients
A Polimeni, I Leo, C Spaccarotella, A Mongiardo… - Scientific Reports, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) is a highly contagious disease that
appeared in China in December 2019 and spread rapidly around the world. Several patients …
appeared in China in December 2019 and spread rapidly around the world. Several patients …
Prognostic parameters of in‐hospital mortality in COVID‐19 patients—An Italian experience
M Ruscica, C Macchi, S Iodice… - European journal of …, 2021 - Wiley Online Library
Abstract Background During COVID‐19 outbreak, Italy was the first country in Europe to be
heavily affected with an intensive care unit mortality of 26%. In order to reduce this …
heavily affected with an intensive care unit mortality of 26%. In order to reduce this …