The objective of the present study was to review recent epidemiological and clinical data on
the association between selected minerals and trace elements and osteoporosis, as well as …

Calcium is responsible for the effectiveness of various processes, and its supply in the diet is
necessary for the normal function of the human body. Apart from being an important …

Besides the two canonical calciotropic hormones, namely parathyroid hormone and 1, 25-
dihydroxyvitamin D [1, 25 (OH) 2 D 3], there are several other endocrine and paracrine …

Mitochondrial iron is indispensable for heme biosynthesis and iron–sulfur cluster assembly.
Several mitochondrial transmembrane proteins have been implicated to function in the …

Thalassemia is a chronic congenital disease characterized by a combination of endocrine
and metabolic disorders. Bone disease is a very common complication related to the poor …

One of the potential contributing factors for iron overload-induced osteoporosis is the iron
toxicity on bone forming cells, osteoblasts. In this study, the comparative effects of Fe3+ and …

Iron overload is the accumulation of excess iron in the body that may occur as a result of
various genetic disorders or as a consequence of repeated blood transfusions. The surplus …

Ca 2+ has an important role in the maintenance of the skeleton and is involved in the main
physiological processes. Its homeostasis is controlled by the intestine, kidney, bone and …

Understanding the underlying molecular mechanism of transporter activity is one of the
major discussions in structural biology. A transporter can exclusively transport one ion …

The consumption of high-fat diets (HFD) and an imbalance in gut microbiome are linked to
obesity. However, the intricate connection between them and the underlying mechanisms …