For three decades, the US Public Health Service has recommended that all persons capable
of becoming pregnant consume 400 μg/day of folic acid (FA) to prevent neural tube defects …

Background Cognitive impairment, including dementia, is a major health concern with the
increasing aging population. Preventive measures to delay cognitive decline are of utmost …

Moderately elevated plasma total homocysteine (tHcy) is a strong modifiable risk factor for
vascular dementia and Alzheimer's disease. Prospectively, elevated tHcy is associated with …

Objective To increase understanding of the biological mechanisms underlying the
association, we investigated the individual relations to cognitive decline of the primary …

Abstract Vitamin B 12 (B12; also known as cobalamin) is a B vitamin that has an important
role in cellular metabolism, especially in DNA synthesis, methylation and mitochondrial …

Background: Many biological, behavioral, social, and environmental factors may contribute
to the delay or prevention of cognitive decline. Purpose: To summarize evidence about …

If you change your brain, you can change your life. Great teachers like the Buddha, Jesus,
Moses, Mohammed, and Gandhi were all born with brains built essentially like anyone else's …

The biosynthesis of B 12, involving up to 30 different enzyme-mediated steps, only occurs in
bacteria. Thus, most eukaryotes require an external source of B 12, and yet the vitamin …

Background Vitamins and minerals play multiple functions within the central nervous system
which may help to maintain brain health and optimal cognitive functioning. Supplementation …

Background: This review examines the associations between low vitamin B12 levels,
neurodegenerative disease, and cognitive impairment. The potential impact of comorbidities …