Genomic inference of a severe human bottleneck during the Early to Middle Pleistocene transition
Population size history is essential for studying human evolution. However, ancient
population size history during the Pleistocene is notoriously difficult to unravel. In this study …
population size history during the Pleistocene is notoriously difficult to unravel. In this study …
Database resources of the national genomics data center in 2020
Nucleic acids research, 2020 - academic.oup.com
Abstract The National Genomics Data Center (NGDC) provides a suite of database
resources to support worldwide research activities in both academia and industry. With the …
resources to support worldwide research activities in both academia and industry. With the …
Successes and failures of immunotherapy for gastric cancer
Highlights•Clinical studies of first-line immunotherapy for gastric cancer were
comprehensively reviewed.•The reasons for failure from a new perspective—chemotherapy …
comprehensively reviewed.•The reasons for failure from a new perspective—chemotherapy …
From asymmetrical to balanced genomic diversification during rediploidization: subgenomic evolution in allotetraploid fish
A persistent enigma is the rarity of polyploidy in animals, compared to its prevalence in
plants. Although animal polyploids are thought to experience deleterious genomic chaos …
plants. Although animal polyploids are thought to experience deleterious genomic chaos …
Chromatin accessibility landscape and regulatory network of high-altitude hypoxia adaptation
High-altitude adaptation of Tibetans represents a remarkable case of natural selection
during recent human evolution. Previous genome-wide scans found many non-coding …
during recent human evolution. Previous genome-wide scans found many non-coding …
The highest-elevation frog provides insights into mechanisms and evolution of defenses against high UV radiation
TT Fu, YB Sun, W Gao, CB Long… - Proceedings of the …, 2022 - National Acad Sciences
Defense against ultraviolet (UV) radiation exposure is essential for survival, especially in
high-elevation species. Although some specific genes involved in UV response have been …
high-elevation species. Although some specific genes involved in UV response have been …
OmicsSuite: a customized and pipelined suite for analysis and visualization of multi-omics big data
With the advancements in high-throughput sequencing technologies such as Illumina,
PacBio, and 10X Genomics platforms, and gas/liquid chromatography-mass spectrometry …
PacBio, and 10X Genomics platforms, and gas/liquid chromatography-mass spectrometry …
[PDF][PDF] Genomic consequences of population decline in critically endangered pangolins and their demographic histories
JY Hu, ZQ Hao, L Frantz, SF Wu, W Chen… - National Science …, 2020 - academic.oup.com
Pangolins are among the most critically endangered animals due to heavy poaching and
worldwide trafficking. However, their demographic histories and the genomic consequences …
worldwide trafficking. However, their demographic histories and the genomic consequences …
Exogenous Melatonin Attenuates Post-Harvest Decay by Increasing Antioxidant Activity in Wax Apple (Syzygium samarangense)
Wax apple is one of the most popular tropical fruit but undergoes serious post-harvest decay
during storage, transportation and marketing. Melatonin (MT) plays important roles in plant …
during storage, transportation and marketing. Melatonin (MT) plays important roles in plant …
Phenotypic and genomic adaptations to the extremely high elevation in plateau zokor (Myospalax baileyi)
The evolutionary outcomes of high elevation adaptation have been extensively described.
However, whether widely distributed high elevation endemic animals adopt uniform …
However, whether widely distributed high elevation endemic animals adopt uniform …